CymitQuimica logo

CAS 16499-58-4

:

7-(Trifluoromethyl)-4(3H)-quinazolinone

Description:
7-(Trifluoromethyl)-4(3H)-quinazolinone is a heterocyclic organic compound characterized by its quinazolinone structure, which consists of a fused benzene and pyrimidine ring system. The presence of a trifluoromethyl group at the 7-position significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. This compound typically exhibits a solid state at room temperature and is soluble in organic solvents. It is often utilized in medicinal chemistry due to its potential pharmacological applications, including anti-inflammatory and anticancer activities. The trifluoromethyl group is known to enhance metabolic stability and bioactivity, making such compounds of interest in drug design. Additionally, the compound may participate in various chemical reactions, including nucleophilic substitutions and cyclization processes, due to the reactivity of the quinazolinone moiety. Safety and handling precautions should be observed, as with many fluorinated compounds, due to potential toxicity and environmental concerns.
Formula:C9H5F3N2O
InChI:InChI=1S/C9H5F3N2O/c10-9(11,12)5-1-2-6-7(3-5)13-4-14-8(6)15/h1-4H,(H,13,14,15)
InChI key:InChIKey=PPQZFZZPLINSJL-UHFFFAOYSA-N
SMILES:O=C1C=2C(=CC(C(F)(F)F)=CC2)NC=N1
Synonyms:
  • 4(1H)-Quinazolinone, 7-(trifluoromethyl)-
  • 4(3H)-Quinazolinone, 7-(trifluoromethyl)-
  • 7-(Trifluoromethyl)-4(3H)-quinazolinone
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 3 products.