CAS 16503-22-3

NALPHA-METHYLHISTAMINE DIHYDROCHLORIDE

Description:

N-alpha-methylhistamine dihydrochloride is a chemical compound that serves as a selective agonist for histamine receptors, particularly the H3 receptor. It is a derivative of histamine, which is a biogenic amine involved in various physiological processes, including immune responses and neurotransmission. This compound is typically encountered as a white to off-white crystalline powder and is soluble in water, making it suitable for various biological applications. Its dihydrochloride form indicates the presence of two hydrochloride ions, which enhance its solubility and stability. N-alpha-methylhistamine dihydrochloride is primarily used in research settings to study the role of histamine in the central nervous system and its potential therapeutic implications in conditions such as allergies, gastric acid secretion, and neurological disorders. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance, to ensure proper laboratory practices.

Formula: C₆H₁₃Cl₂N₃

InChI: InChI=1/C6H11N3.2ClH/c1-7-3-2-6-4-8-5-9-6;;/h4-5,7H,2-3H2,1H3,(H,8,9);2*1H

SMILES: CNCCc1cnc[nH]1.Cl.Cl

Synonyms:

• 1H-Imidazole-4-ethanamine, N-methyl-, hydrochloride (1:2)
• 2-(1H-Imidazol-4-yl)-N-methylethanamine dihydrochloride

[2-(1H-imidazol-4-yl)ethyl](methyl)amine dihydrochloride

CAS: 16503-22-3

Formula: C₆H₁₃Cl₂N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 198.0935

Ref: IN-DA001V84

N-Methylhistamine (dihydrochloride)

CAS: 16503-22-3

N-Methylhistamine (dihydrochloride)

Purity: 98%

Molecular weight: 198.09g/mol

Ref: 54-OR1075582

Nα-Methylhistamine dihydrochloride

CAS: 16503-22-3

Formula: C₆H₁₁N₃·2HCl

Molecular weight: 198.09

Ref: 7W-GK2472

N-a-Methylhistamine Dihydrochloride

Controlled Product

CAS: 16503-22-3

Stability Hygroscopic
Applications Nalpha-Methylhistamine Dihydrochloride is a H2 receptor agonist.
References Lappin, D., et al.: Clin. Exp. Immunol., 41, 497-504 (1980); Durant, G. J., et al.: J. Med. Chem., 19, 923-928 (1976)

Formula: C₆H₁₁N₃·2HCl

Color and Shape: Neat

Molecular weight: 125.17 +(72.92)

Ref: TR-B496303

N±-Methylhistamine dihydrochloride

CAS: 16503-22-3

N±-Methylhistamine dihydrochloride is a metabolite of histamine that has been shown to be produced in mononuclear phagocytes by the oxidation of histamine. N±-Methylhistamine dihydrochloride has been shown to cause oxidative damage to cells, and causes cell response, which may lead to radical formation. It has also been shown to damage DNA and RNA.

Formula: C₆H₁₁N₃·2HCl

Purity: Min. 95%

Molecular weight: 198.09 g/mol

Ref: 3D-RAA50322

Nα-Methylhistamine dihydrochloride

CAS: 16503-22-3

Nα-Methylhistamine dihydrochloride is a histamine H3 receptor agonist.

Formula: C₆H₁₃Cl₂N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 198.094

Ref: TM-T23038