CAS 16503-32-5: Brevilin A

Description: Brevilin A is a natural compound classified as a sesquiterpene lactone, primarily derived from the plant species *Centipeda minima*. It is known for its potential pharmacological properties, including anti-inflammatory, antimicrobial, and anticancer activities. The molecular structure of Brevilin A features a unique bicyclic framework, which contributes to its biological activity. This compound has garnered interest in medicinal chemistry due to its ability to modulate various biological pathways, making it a candidate for further research in drug development. Additionally, Brevilin A exhibits a relatively low toxicity profile, which is advantageous for therapeutic applications. Its solubility characteristics can vary, influencing its bioavailability and efficacy in biological systems. Overall, Brevilin A represents a significant area of study within natural product chemistry, with ongoing investigations aimed at elucidating its mechanisms of action and potential therapeutic uses.

Formula: C₂₀H₂₆O₅

InChI: InChI=1S/C20H26O5/c1-6-10(2)18(22)25-17-16-12(4)19(23)24-14(16)9-11(3)13-7-8-15(21)20(13,17)5/h6-8,11-14,16-17H,9H2,1-5H3/b10-6-/t11-,12+,13+,14-,16-,17+,20+/m1/s1

InChI key: InChIKey=KUPPZVXLWANEJJ-UXPPPGSFSA-N

SMILES: O=C(OC1C2C(OC(=O)C2C)CC(C)C3C=CC(=O)C13C)C(=CC)C

Synonyms:

• 2-Butenoic acid, 2-methyl-, (3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester, (2Z)-
• 2-Butenoic acid, 2-methyl-, 2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester, [3S-[3α,3aβ,4β(Z),4aα,7aβ,8β,9aβ]]-
• 2-Butenoicacid, 2-methyl-,2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-ylester, [3S-[3a,3ab,4b(Z),4aa,7ab,8b,9ab]]-
• 6-O-Angeloylplenolin
• 6-O-Angeloylprenolin
• Ambros-2-en-12-oic acid, 6a,8b-dihydroxy-4-oxo-, 12,8-lactone, 2-methylcrotonate, (Z)- (8CI)
• Ambros-2-en-12-oic acid, 6α,8β-dihydroxy-4-oxo-, 12,8-lactone, 2-methylcrotonate, (Z)-
• Azuleno[6,5-b]furan, 2-butenoic acid deriv.
• Brevelin A
• Brevilin A

2-Butenoic acid, 2-methyl-, (3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-yl ester, (2Z)-

CAS: 16503-32-5

• Formula: C₂₀H₂₆O₅
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 346.4174

Brevilin A

CAS: 16503-32-5

• Purity: ≥98%
• Molecular weight: 346.42g/mol

Brevilin A

CAS: 16503-32-5

• Formula: C₂₀H₂₆O₅
• Molecular weight: 346.42

Brevilin A

CAS: 16503-32-5

• Purity: 98%
• Molecular weight: 346.42g/mol

Brevilin A

CAS: 16503-32-5

​Brevilin A is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic …

• Formula: C₂₀H₂₆O₅
• Purity: 95%~99%
• Molecular weight: 346.423

Brevilin A

CAS: 16503-32-5

Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis …

• Formula: C₂₀H₂₆O₅
• Purity: 100% - 99.74%
• Color and Shape: Solid
• Molecular weight: 346.42

Brevilin a

CAS: 16503-32-5

Lactone

• Formula: C₂₀H₂₆O₅
• Purity: ≥ 90.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 346.42