CAS 1651-29-2

6-Chloro-2-fluoropurine

Description:

6-Chloro-2-fluoropurine is a purine derivative characterized by the presence of chlorine and fluorine substituents on its aromatic ring. This compound features a chlorine atom at the 6-position and a fluorine atom at the 2-position of the purine structure, which is a bicyclic compound consisting of fused imidazole and pyrimidine rings. It is typically a white to off-white solid and is soluble in polar organic solvents. The presence of halogen atoms can influence its reactivity, making it a potential candidate for various chemical reactions, including nucleophilic substitutions. 6-Chloro-2-fluoropurine is of interest in medicinal chemistry, particularly in the development of antiviral and anticancer agents, due to its ability to interfere with nucleic acid synthesis. Its molecular structure allows it to mimic natural purines, which can lead to its incorporation into nucleic acids, potentially disrupting normal cellular processes. Safety and handling precautions should be observed, as with many halogenated compounds, due to potential toxicity and environmental concerns.

Formula: C₁₁H₇F₁₇O

InChI: InChI=1/C11H7F17O/c12-4(13,2-1-3-29)5(14,15)6(16,17)7(18,19)8(20,21)9(22,23)10(24,25)11(26,27)28/h29H,1-3H2

SMILES: C(CC(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)CO

Synonyms:

• 6-chloro-2-fluoro-5H-purine
• 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoroundecan-1-Ol
• 6-chloro-2-fluoro-7H-purine

6-Chloro-2-fluoropurine

CAS: 1651-29-2

Formula: C₅H₂ClFN₄

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Light yellow to Green powder to crystal

Molecular weight: 172.55

Ref: 3B-C2221

6-Chloro-2-fluoropurine, 97%

CAS: 1651-29-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₅H₂ClFN₄

Purity: 97%

Color and Shape: White to cream to pale brown, Powder, crystals, crystalline powder and/or chunks

Molecular weight: 172.55

Ref: 02-H25825

9H-Purine, 6-chloro-2-fluoro-

CAS: 1651-29-2

Formula: C₅H₂ClFN₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 172.5476

Ref: IN-DA001V9R

6-Chloro-2-fluoro-9H-purine

CAS: 1651-29-2

6-Chloro-2-fluoro-9H-purine

Formula: C₅H₂ClFN₄

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 172.55g/mol

Ref: 54-PC7945

6-Chloro-2-fluoropurine

CAS: 1651-29-2

6-Cl-2-F-purine: used in CDK inhibitors & anti-HIV/HBV agents synthesis.

Formula: C₅H₂ClFN₄

Color and Shape: Solid

Molecular weight: 172.55

Ref: TM-T37065

6-Chloro-2-fluoro-7H-purine

CAS: 1651-29-2

6-Chloro-2-fluoro-7H-purine

Purity: 97%

Molecular weight: 172.55g/mol

Ref: 54-PC408500

6-Chloro-2-fluoropurine

CAS: 1651-29-2

Formula: C₅H₂ClFN₄

Purity: 97%

Color and Shape: Solid, Powder or Crystalline Powder or Chunks

Molecular weight: 172.55

Ref: 10-F009088

6-Chloro-2-fluoropurine

CAS: 1651-29-2

Formula: C₅H₂ClFN₄

Molecular weight: 172.55

Ref: ST-EA-CP-F71016

6-Chloro-2-fluoropurine

CAS: 1651-29-2

6-Chloro-2-fluoropurine is an analytical reagent with a monoclonal antibody that binds to the nucleic acid of HL-60 cells and can be used for optical analysis. 6-Chloro-2-fluoropurine has been shown to have significant cytotoxicity against HL-60 cells, which may be due to its ability to bind to intracellular targets. 6-Chloro-2-fluoropurine has also been shown to inhibit the growth of HL-60 cells in a fluorescein angiography study and is used as a diagnostic agent for diagnosis of cancer.

Formula: C₅H₂ClFN₄

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 172.55 g/mol

Ref: 3D-FC03333