CAS 1652561-87-9

SAH-SOS1A

CAS: 1652561-87-9

KRas/SOS1 inhibitor; binds KRas pocket, Kd 106-176 nM; blocks nucleotide binding; cytotoxic to KRas-driven cancers; disrupts ERK-MAPK pathway; cell-permeable.

Formula: C₁₀₀H₁₅₉N₂₇O₂₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 2187.53

Ref: TM-TP2116

SAH-SOS1A

CAS: 1652561-87-9

SAH-SOS1A is a peptidomimetic that has been shown to activate the pancreatic secretory response, in vitro assays, and cancer cell lines. Activation of the pancreatic secretory response by SAH-SOS1A has been shown to be due to its ability to inhibit the activity of effector proteins. It has been shown to have a higher potency than sapanisertib, which is an inhibitor of the sarcoma viral oncogene. Further research has shown that SAH-SOS1A is able to inhibit coagulation in human cancer cells, while also having no toxicity in normal human cells.

Formula: C₁₀₀H₁₅₉N₂₇O₂₈

Purity: Min. 95%

Molecular weight: 2,187.5 g/mol

Ref: 3D-CRC56187