CAS 1656-44-6

2,4-Dinitrobenzenesulfonyl chloride

Description:

2,4-Dinitrobenzenesulfonyl chloride, with the CAS number 1656-44-6, is a chemical compound characterized by its sulfonyl chloride functional group and two nitro groups positioned on a benzene ring. This compound is typically a yellow crystalline solid that is soluble in organic solvents such as dichloromethane and acetone but is generally insoluble in water. It is known for its reactivity, particularly in nucleophilic substitution reactions, where it can act as a sulfonating agent. The presence of the nitro groups enhances its electrophilic character, making it useful in various synthetic applications, including the preparation of sulfonamides and other derivatives. Due to its reactive nature, it must be handled with care, as it can be corrosive and may pose health hazards upon exposure. Proper safety measures, including the use of personal protective equipment, are essential when working with this compound in a laboratory setting.

Formula: C₆H₃ClN₂O₆S

InChI: InChI=1S/C6H3ClN2O6S/c7-16(14,15)6-2-1-4(8(10)11)3-5(6)9(12)13/h1-3H

InChI key: InChIKey=SSFSNKZUKDBPIT-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C(S(Cl)(=O)=O)C=CC(N(=O)=O)=C1

Synonyms:

• 2,4-Dinitrobenzene-1-sulfonyl chloride
• 2,4-Dinitrobenzenesulphonyl chloride
• 2,4-Dinitrophenylsulfonyl chloride
• Benzenesulfonyl chloride, 2,4-dinitro-
• 2,4-Dinitrobenzenesulfonyl chloride

2,4-Dinitrobenzenesulfonyl chloride, 98%

CAS: 1656-44-6

2,4-Dinitrobenzenesulfonyl chloride was used to protect primary amines. It was used as starting reagent in the synthesis of tert-butyl 2-[(2,4-dinitrophenyl) sulfonyl]amino acetate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documenta

Formula: C₆H₃ClN₂O₆S

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder or granules, Cream to yellow to pale brown

Molecular weight: 266.61

Ref: 02-B23035

2,4-Dinitrobenzenesulphonyl chloride

CAS: 1656-44-6

2,4-Dinitrobenzenesulphonyl chloride

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 266.62g/mol

Ref: 54-OR30499

2,4-Dinitrobenzenesulfonyl chloride

CAS: 1656-44-6

Formula: C₆H₃ClN₂O₆S

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 266.61

Ref: 10-F050910

2,4-Dinitrophenylsulfonyl Chloride

Controlled Product

CAS: 1656-44-6

Stability Hygroscopic
Applications 2,4-Dinitrophenylsulfonyl Chloride, can be used to protect primary amines. It is also used as starting material in the synthesis of tert-butyl 2-[(2,4-dinitrophenyl) sulfonyl]aminoacetate.
References Rachel J Ball et. al.: Artificial DNA, PNA & XNA, 1(1), undefined (2011-6-21);

Formula: C₆H₃ClN₂O₆S

Color and Shape: Light Yellow

Molecular weight: 266.62

Ref: TR-D426820

2,4-Dinitrobenzenesulfonyl chloride

CAS: 1656-44-6

2,4-Dinitrobenzenesulfonyl chloride is a chemical reagent that is used in analytical chemistry. It reacts with pyrazole rings to form 2-aminopyridine derivatives. The reaction can be enhanced by adding metal ions such as copper(II) or zinc(II). 2,4-Dinitrobenzenesulfonyl chloride is also used in the solid-phase synthesis of heterocycles and in the synthesis of pharmaceuticals. The compound has been shown to react with human serum and form an unstable intermediate that undergoes hydrolysis to produce sulfate ion and trifluoroacetic acid. This reaction mechanism can be applied to other nucleophilic compounds such as bromide ion. 2,4-Dinitrobenzenesulfonyl chloride reacts with the amine group of proteins using the S N 1 mechanism. The resulting product is a chlorinated amino acid derivative which exhibits fluorescence properties when reacted with

Formula: C₆H₃ClN₂O₆S

Purity: Min. 95%

Molecular weight: 266.62 g/mol

Ref: 3D-FD00408