CAS 165669-14-7

3-Chloro-7-nitro-1H-indole

Description:

3-Chloro-7-nitro-1H-indole is a chemical compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of a chlorine atom at the 3-position and a nitro group at the 7-position contributes to its unique reactivity and properties. This compound is typically a solid at room temperature and may exhibit a range of colors depending on its purity and form. It is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the presence of the nitro group, which can participate in various chemical reactions. The chlorine substituent can also influence the compound's biological activity and solubility. As with many nitro-containing compounds, 3-Chloro-7-nitro-1H-indole may be sensitive to light and heat, necessitating careful handling and storage. Safety data sheets should be consulted for information on toxicity and environmental impact, as halogenated and nitro compounds can pose risks in certain contexts.

Formula: C₈H₅ClN₂O₂

InChI: InChI=1S/C8H5ClN2O2/c9-6-4-10-8-5(6)2-1-3-7(8)11(12)13/h1-4,10H

InChI key: InChIKey=QDGYVAQMPDTWIE-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C2C(C(Cl)=CN2)=CC=C1

Synonyms:

• 1H-Indole, 3-chloro-7-nitro-
• 3-Chloro-7-Nitro-Indole
• 3-Chloro-7-nitroindole
• 3-Chloro-7-nitro-1H-indole

1H-Indole, 3-chloro-7-nitro-

CAS: 165669-14-7

Formula: C₈H₅ClN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 196.5905

Ref: IN-DA001WAO

3-Chloro-7-nitroindole

CAS: 165669-14-7

3-Chloro-7-nitroindole

Purity: 95%

Molecular weight: 196.59g/mol

Ref: 54-OR912798

3-Chloro-7-nitro-indole

CAS: 165669-14-7

Formula: C₈H₅ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 196.59

Ref: 10-F040495

3-Chloro-7-nitro-1H-indole

CAS: 165669-14-7

3-Chloro-7-nitro-1H-indole is a chemical compound that has been shown to have antitumor activity in clinical trials. It is catalysed by the addition of chloride ions to the nitro group, yielding an aminocarbonyl intermediate. This intermediate reacts with hydrogen chloride to form a chlorinating agent that can react with DNA and protein bases. The chlorinating agent has been shown to be efficient in screening for anticancer drugs. 3-Chloro-7-nitro-1H-indole is currently being tested for efficacy against colon carcinoma cells and human colon carcinoma xenografts.

Formula: C₈H₅ClN₂O₂

Purity: Min. 95%

Molecular weight: 196.59 g/mol

Ref: 3D-FC147708