CAS 165739-62-8

Loratadine N-Oxide

Description:

Loratadine N-Oxide is a chemical compound derived from loratadine, an antihistamine commonly used to treat allergies. It is characterized by its structural modification, where an N-oxide functional group is introduced, affecting its pharmacological properties. This compound typically appears as a white to off-white solid and is soluble in organic solvents. Loratadine N-Oxide is known for its potential to exhibit antihistaminic activity, although its efficacy and safety profile may differ from that of its parent compound, loratadine. The presence of the N-oxide group can influence the compound's metabolism and interaction with biological systems. As with many pharmaceutical compounds, understanding its characteristics, including stability, solubility, and biological activity, is crucial for its application in therapeutic contexts. Research into its specific pharmacokinetics and pharmacodynamics continues to enhance the understanding of its role in allergy treatment and potential side effects.

Formula: C₂₂H₂₃ClN₂O₃

InChI: InChI=1/C22H23ClN2O3/c1-2-28-22(26)24-12-9-15(10-13-24)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-25(27)21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3

Synonyms:

• 4-(8-Chloro-5,6-dihydro-1-oxido-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester
• Sch 38554

Loratadine N-Oxide

CAS: 165739-62-8

Formula: C₂₂H₂₃ClN₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 398.89

Ref: 4Z-L-1066

Loratadine N-Oxide

CAS: 165739-62-8

Formula: C₂₂H₂₃ClN₂O₃

Color and Shape: Neat

Molecular weight: 398.88

Ref: 86-MM0257.21

Loratadine N-Oxide

Controlled Product

CAS: 165739-62-8

Applications Loratadine N-oxide nonsedating-type histamine.

Formula: C₂₂H₂₃ClN₂O₃

Color and Shape: Neat

Molecular weight: 398.88

Ref: TR-L469595

Loratadine N-Oxide

CAS: 165739-62-8

Formula: C₂₂H₂₃ClN₂O₃

Molecular weight: 398.89

Ref: ST-EA-CP-L5010

Loratadine N-oxide

CAS: 165739-62-8

Loratadine N-oxide is an organic chemical compound that is used as a reagent, complex compound, and useful intermediate. It has CAS No. 165739-62-8 and a molar mass of 280.2 g/mol. The solid form is white to pale yellow in color. It can be used as a building block for other compounds or as a versatile building block for reactions such as the synthesis of pharmaceuticals, pesticides, agrochemicals, and polymers. Loratadine N-oxide is also used in research chemicals and speciality chemicals due to its wide range of applications in various industries.

Formula: C₂₂H₂₃ClN₂O₃

Purity: Min. 95%

Molecular weight: 398.88 g/mol

Ref: 3D-FL24934

Loratadine N-oxide

CAS: 165739-62-8

Loratadine N-oxide is a metabolite of the histamine H1 receptor inverse agonist loratadine.

Formula: C₂₂H₂₃ClN₂O₃

Color and Shape: Solid

Molecular weight: 398.88

Ref: TM-T70306