CAS 16599-33-0

S-(2-aminoethyl) methanesulfonothioate

Description:

S-(2-aminoethyl) methanesulfonothioate, with the CAS number 16599-33-0, is a chemical compound characterized by its sulfonothioate functional group, which includes a methanesulfonyl moiety attached to a thioether. This compound features an aminoethyl side chain, contributing to its potential as a biological or pharmaceutical agent. It is typically a colorless to pale yellow liquid or solid, depending on its purity and form. The presence of the amino group suggests that it may participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Its sulfonothioate structure may impart unique properties, such as increased solubility in polar solvents and potential reactivity with electrophiles. This compound may also exhibit biological activity, making it of interest in medicinal chemistry and biochemistry. Safety data should be consulted for handling and storage, as compounds with similar functional groups can exhibit toxicity or irritant properties. Overall, S-(2-aminoethyl) methanesulfonothioate is a versatile compound with potential applications in various fields of research.

Formula: C₃H₉NO₂S₂

InChI: InChI=1/C3H9NO2S2/c1-8(5,6)7-3-2-4/h2-4H2,1H3

SMILES: CS(=O)(=O)SCCN

Synonyms:

• methanesulfonothioic acid, S-(2-aminoethyl) ester

S-(2-Aminoethyl) methanethiosulphonate hydrobromide

CAS: 16599-33-0

S-(2-Aminoethyl) methanethiosulphonate hydrobromide

Formula: C₃H₉NO₂S₂·BrH

Purity: ≥95%

Color and Shape: off-white solid

Molecular weight: 236.15g/mol

Ref: 54-OR0910T

2-Aminoethyl Methanethiosulfonate Hydrobromide

Controlled Product

CAS: 16599-33-0

Stability Hygroscopic
Applications 2-Aminoethyl Methanethiosulfonate Hydrobromide reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.
References Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996) Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Egan, T.M., et al.: The Journal of Neuroscience, 18(7), 2350 (1998), Lin, C.-W. and Tsung-Yu, C.: J. Gen. Physiol., 116, 535 (2000)

Formula: C₃H₉NO₂S₂·BrH

Color and Shape: Neat

Molecular weight: 236.15

Ref: TR-A609100

2-Aminoethyl methanethiosulfonate hydrobromide

CAS: 16599-33-0

2-Aminoethyl methanethiosulfonate hydrobromide (2AMTSH) is an alkylating agent that inhibits the uptake of creatine in the brain. It has been shown to inhibit the transport of creatine across the apical membrane of granule neurons in Xenopus oocytes, which is mediated by a sodium-dependent, electroneutral transporter. 2AMTSH also binds to basic proteins and prevents their activation by blocking the binding of ATP. This inhibition leads to a decrease in cellular energy production and may be responsible for some of the effects observed in mice. The therapeutic potential for 2AMTSH is limited due to its toxicity, but it may be useful as a nutritional supplement for those with creatine deficiencies.

Formula: C₃H₁₀BrNO₂S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 236.15 g/mol

Ref: 3D-RAA59933

MTSEA hydrobromide

CAS: 16599-33-0

MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain similar in size to lysine.

Formula: C₃H₁₀BrNO₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.15

Ref: TM-T19437