CAS 1660-95-3

Tetraisopropyl methylenediphosphonate

Description:

Tetraisopropyl methylenediphosphonate, with the CAS number 1660-95-3, is an organophosphorus compound characterized by its structure, which includes two phosphonate groups linked by a methylene bridge. This compound is typically a colorless to pale yellow liquid and is known for its high stability and low volatility. It is soluble in organic solvents, making it useful in various chemical applications, including as a reagent in organic synthesis and as a potential flame retardant. The presence of isopropyl groups contributes to its steric hindrance, which can influence its reactivity and interactions with other substances. Additionally, tetraisopropyl methylenediphosphonate exhibits properties that may be beneficial in agricultural chemistry, particularly in the development of herbicides or pesticides. However, like many organophosphorus compounds, it should be handled with care due to potential toxicity and environmental concerns. Proper safety measures and regulations should be observed when working with this substance in laboratory or industrial settings.

Formula: C₁₃H₃₀O₆P₂

InChI: InChI=1/C13H30O6P2/c1-10(2)16-20(14,17-11(3)4)9-21(15,18-12(5)6)19-13(7)8/h10-13H,9H2,1-8H3

InChI key: InChIKey=ODTQUKVFOLFLIQ-UHFFFAOYSA-N

SMILES: P(CP(OC(C)C)(OC(C)C)=O)(OC(C)C)(OC(C)C)=O

Synonyms:

• 2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane
• Methylenediphosphonic acid tetraisopropyl ester
• NSC 226577
• Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetrakis(1-methylethyl) ester
• Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester
• Phosphonic acid, methylenedi-, tetraisopropyl ester
• Tetraisopropyl methylenebisphosphonate
• Tetraisopropylmethylenediphosphonate
• Tetrakis(O-isopropyl) methylenediphosphonate
• Tetrapropan-2-Yl Methanediylbis(Phosphonate)
• [(Diisopropoxyphosphinyl)methyl]diisopropoxyphosphine oxide
• Tetraisopropyl methylenediphosphonate
• Bis(diisopropoxyphosphinyl)methane
• phosphonicacid,methylenebis-,tetrakis(1-methylethyl)ester
• Methanediphosphonic acid tetraisopropyl ester
• METHYLENEBIS-PHOSPHONICACID,TETRAKIS(1-METHYLETHYL)ESTER
• tetra-i-Propylmethylenediphosphonate
• METHYLENEPHOSPHONIC ACID TETRAISOPROPYL ESTER
• Tetraisopropyl Methylenediphonate
• Tetra isopropyl methylene diphospshonate
• Tetraisopropyl(methylene)bisphosphonate, 98 %

Tetraisopropyl Methylenediphosphonate

CAS: 1660-95-3

Formula: C₁₃H₃₀O₆P₂

Purity: >97.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 344.32

Ref: 3B-M1319

Tetraisopropyl methylenediphosphonate, 98%

CAS: 1660-95-3

Tetraisopropyl methylenediphosphonate is used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase. It is also used in the preparation of E2-bisphosphonate conjugates. This Thermo Scientific Chemicals brand product was originally part of

Formula: C₁₃H₃₀O₆P₂

Purity: 98%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 344.33

Ref: 02-A13484

MEDRONIC ACID IMPURITY B CRS

CAS: 1660-95-3

MEDRONIC ACID IMPURITY B CRS

Ref: 41-Y0001106

Phosphonic acid, P,​P'-​methylenebis-​, P,​P,​P',​P'-​tetrakis(1-​methylethyl) ester

CAS: 1660-95-3

Formula: C₁₃H₃₀O₆P₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 344.3212

Ref: IN-DA003UPF

Tetraisopropyl methylenediphosphonate

CAS: 1660-95-3

Formula: C₁₃H₃₀O₆P₂

Purity: ≥ 97.5%

Color and Shape: Clear, colourless to light-yellow liquid

Molecular weight: 344.32

Ref: 7W-GX8847

Tetraisopropyl (methylene)bisphosphonate

CAS: 1660-95-3

Tetraisopropyl (methylene)bisphosphonate

Purity: 98%

Molecular weight: 344.32g/mol

Ref: 54-OR10802

Tetrakis(1-methylethyl) Methylenediphosphonate

Controlled Product

CAS: 1660-95-3

Formula: C₁₃H₃₀O₆P₂

Color and Shape: Neat

Molecular weight: 344.32

Ref: 86-MM3503.02

Tetraisopropyl Methylenediphosphonate

Controlled Product

CAS: 1660-95-3

Applications Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.
References Wang, G. et al.: J. Med. Chem., 47, 6902 (2004); Gil, L. et al.: Bioorg. Med. Chem., 7, 901 (1999);

Formula: C₁₃H₃₀O₆P₂

Color and Shape: Neat

Molecular weight: 344.32

Ref: TR-T296270

Tetraisopropyl methylenebis(phosphonate)

CAS: 1660-95-3

Purity: 98%

Molecular weight: 344.15

Ref: 10-F551682

Tetraisopropyl methylenediphosphonate

CAS: 1660-95-3

Tetraisopropyl methylenediphosphonate is a colorant that is used in the manufacture of dyes, paints and other products. It is also used as a reagent to synthesize new compounds with nitrogen-containing groups. Tetraisopropyl methylenediphosphonate is formed by the reaction of hydrochloric acid with a diazonium salt, such as nitrobenzene. This compound can be oxidized to form tetraisopropyl methylenediphosphonic acid (TIMP) in the presence of chloride. TIMP has been shown to have effects on bone resorption and heart disease. The mechanism of action for this compound is not yet fully known, but it may inhibit the growth factor involved in bone resorption or affect cardiac cells.

Formula: C₁₃H₃₀O₆P₂

Purity: Min. 95%

Molecular weight: 344.32 g/mol

Ref: 3D-FT73261