CAS 1660117-38-3

3(2H)-Pyridazinone, 2,4-dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-

Description:

3(2H)-Pyridazinone, 2,4-dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]- is a complex organic compound characterized by its multi-cyclic structure, which includes a pyridazinone core and various substituents that contribute to its chemical properties. The presence of the imidazo[4,5-c]pyridine moiety suggests potential biological activity, as compounds with such structures are often investigated for pharmacological applications. The dimethyl groups indicate that the compound may exhibit specific steric and electronic properties, influencing its reactivity and interactions with biological targets. Additionally, the presence of a phenylethyl group and a tetrahydro-2H-pyran moiety may enhance lipophilicity, potentially affecting the compound's solubility and permeability. Overall, this compound's unique structural features suggest it may have interesting chemical behavior and potential applications in medicinal chemistry, although specific biological activities would require further investigation through experimental studies.

Formula: C₂₅H₂₇N₅O₂

InChI: InChI=1S/C25H27N5O2/c1-16-13-21(28-29(3)25(16)31)24-27-22-15-26-20(19-9-11-32-12-10-19)14-23(22)30(24)17(2)18-7-5-4-6-8-18/h4-8,13-15,17,19H,9-12H2,1-3H3/t17-/m0/s1

InChI key: InChIKey=QNFGQQDKBYVNAS-KRWDZBQOSA-N

SMILES: [C@@H](C)(N1C(=NC=2C1=CC(=NC2)C3CCOCC3)C=4C=C(C)C(=O)N(C)N4)C5=CC=CC=C5

Synonyms:

• BI 894999
• 3(2H)-Pyridazinone, 2,4-dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-
• 2,4-Dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-3(2H)-pyridazinone

BRD4 Inhibitor-10

CAS: 1660117-38-3

BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).

Formula: C₂₅H₂₇N₅O₂

Purity: 99.53%

Color and Shape: Solid

Molecular weight: 429.51

Ref: TM-T14776

3(2H)-Pyridazinone, 2,4-dimethyl-6-[1-[(1S)-1-phenylethyl]-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-

CAS: 1660117-38-3

Formula: C₂₅H₂₇N₅O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 429.5142

Ref: IN-DA01PR6J

BRD4 Inhibitor-10

CAS: 1660117-38-3

BRD4 Inhibitor-10

Purity: ≥98%

Molecular weight: 429.51g/mol

Ref: 54-BUP08530

(S)-2,4-Dimethyl-6-(1-(1-Phenylethyl)-6-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazo[4,5-c]Pyridin-2-Yl)Pyridazin-3(2H)-One

CAS: 1660117-38-3

(S)-2,4-Dimethyl-6-(1-(1-Phenylethyl)-6-(Tetrahydro-2H-Pyran-4-Yl)-1H-Imidazo[4,5-c]Pyridin-2-Yl)Pyridazin-3(2H)-One

Purity: 97%

Molecular weight: 429.51g/mol

Ref: 54-OR1023847

BET BRD4 inhibitor compound II-25

CAS: 1660117-38-3

BET BRD4 inhibitor compound II-25 belongs to a class of protein inhibitors. It is orally available and can inhibit cancer cells in vitro. BET BRD4 inhibitor compound II-25 has been shown to induce cell maturation and apoptosis in myeloid leukemia cells. This drug also inhibits the methyltransferase activity of the enzyme, thereby preventing the production of inflammatory cytokines that cause inflammation. In addition, this drug has shown potential as an anticancer therapeutic by inhibiting cancer cell proliferation and inducing tumor necrosis in vivo. It is possible that BET BRD4 inhibitor compound II-25 may function as a toll-like receptor modulator because it can block TLR signaling pathways in mice.

Formula: C₂₅H₂₇N₅O₂

Purity: Min. 95%

Molecular weight: 429.51 g/mol

Ref: 3D-KRC11738