CAS 166037-78-1

S-DIDEMETHYL CITALOPRAM

Description:

S-Didemethylcitalopram, with the CAS number 166037-78-1, is a chemical compound that is a derivative of citalopram, an antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class. This substance is characterized by its specific stereochemistry, which plays a crucial role in its pharmacological activity. S-Didemethylcitalopram is known for its potential effects on serotonin levels in the brain, contributing to mood regulation. The compound is typically studied for its therapeutic applications in treating depression and anxiety disorders. In terms of physical properties, like many organic compounds, it may exhibit characteristics such as solubility in organic solvents and specific melting or boiling points, which are important for its formulation and use in pharmaceutical applications. Additionally, understanding its metabolic pathways and interactions with other drugs is essential for assessing its safety and efficacy in clinical settings. Overall, S-Didemethylcitalopram represents a significant area of interest in medicinal chemistry and pharmacology.

Formula: C₁₈H₁₇FN₂O

InChI: InChI=1S/C18H17FN2O/c19-16-5-3-15(4-6-16)18(8-1-9-20)17-7-2-13(11-21)10-14(17)12-22-18/h2-7,10H,1,8-9,12,20H2/t18-/m0/s1

InChI key: InChIKey=RKUKMUWCRLRPEJ-SFHVURJKSA-N

SMILES: C(CCN)[C@@]1(C=2C(CO1)=CC(C#N)=CC2)C3=CC=C(F)C=C3

Synonyms:

• (+)-(S)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
• (1S)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile
• (S)-1-(3-Aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile
• (S)-Didemethylcitalopram
• (S)-Didesmethylcitalopra
• (S)-Didesmethylcitalopram
• 5-Isobenzofurancarbonitrile, 1-(3-aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-
• 5-Isobenzofurancarbonitrile, 1-(3-aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-, (S)-
• N-Desmethylescitalopram
• S-Didesmethylcitalopam
• (S)-Didemethyl CitalopramDISCONTINUED. See D439486

(S)-N-Didesmethyl Citalopram Oxalate

CAS: 166037-78-1

Formula: C₁₈H₁₇FN₂O·C₂H₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 296.35 90.03

Ref: 4Z-C-0919

(S)-Didemethyl Citalopram Hydrochloride (>85%)

Controlled Product

CAS: 1189694-81-2, 166037-78-1

Applications A metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.[α]=+14.1°C
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ahern, D., et al.: Am. J. Cardiol., 66, 59 (1990), von Moltke, L., et al.: Drug Metab. Dispos., 29, 1102 (2001), Serebruany, V., et al.: Pharm. Res., 43, 453 (2001), Serebruany, V., et al.: J. Cardiovasc. Pharmacol., 43, 677 (2004),

Formula: C₁₈H₁₇FN₂O·HCl

Purity: >85%

Color and Shape: Neat

Molecular weight: 296.35 +(36.46)

Ref: TR-D439486

(S)-Didemethyl Citalopram-d6 Hydrochloride

Controlled Product

CAS: 1189694-81-2, 166037-78-1

Formula: C₁₈H₁₁D₆FN₂O•HCl

Color and Shape: Neat

Molecular weight: 338.84

Ref: TR-D439487

(S)-Didemethyl Citalopram

CAS: 166037-78-1

Formula: C₁₈H₁₇FN₂O

Molecular weight: 296.3

Ref: ST-EA-CP-C23040