CAS 166170-15-6

(R)-N-BOC-2-methylproline

Description:

(R)-N-BOC-2-methylproline is a chiral amino acid derivative characterized by its unique structural features. It contains a tert-butyloxycarbonyl (BOC) protecting group, which is commonly used in peptide synthesis to protect the amine group of amino acids. The presence of the 2-methyl group on the proline ring introduces steric hindrance, influencing its conformational properties and reactivity. This compound is typically utilized in organic synthesis and pharmaceutical applications, particularly in the development of peptide-based drugs due to its ability to introduce chirality and enhance biological activity. The BOC group can be easily removed under acidic conditions, allowing for the subsequent functionalization of the amino group. (R)-N-BOC-2-methylproline is soluble in organic solvents, and its stability and reactivity make it a valuable intermediate in the synthesis of more complex molecules. Its specific stereochemistry is crucial for its biological interactions, making it an important compound in medicinal chemistry and drug design.

Formula: C₁₁H₁₉NO₄

InChI: InChI=1S/C11H19NO4/c1-10(2,3)16-9(15)12-7-5-6-11(12,4)8(13)14/h5-7H2,1-4H3,(H,13,14)/t11-/m1/s1

InChI key: InChIKey=YQXRKJHVAUKXRN-LLVKDONJSA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@](C(O)=O)(C)CCC1

Synonyms:

• (2R)-1-[(tert-butoxy)carbonyl]-2-methylpyrrolidine-2-carboxylic acid
• (2R)-2-Methyl-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
• (R)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidine-2-carboxylic acid
• (R)-Boc-2-methylproline
• (R)-N-Boc-2-MethyL proline
• 1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester, (2R)-
• 1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester, (R)-

1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester, (2R)-

CAS: 166170-15-6

Formula: C₁₁H₁₉NO₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 229.2729

Ref: IN-DA001WJI

1-Boc-2-methyl-D-proline

CAS: 166170-15-6

1-Boc-2-methyl-D-proline

Purity: 98%

Molecular weight: 229.28g/mol

Ref: 54-OR75171

1-(tert-butoxycarbonyl)-2-methyl-D-proline

CAS: 166170-15-6

Formula: C₁₁H₁₉NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 229.276

Ref: 10-F312761