CAS 1663-45-2

1,2-Bis(diphenylphosphino)ethane

Description:

1,2-Bis(diphenylphosphino)ethane, commonly referred to as DPPE, is a bidentate ligand widely used in coordination chemistry and catalysis. It features two diphenylphosphino groups attached to a central ethane backbone, which allows it to effectively chelate metal ions. DPPE is characterized by its ability to stabilize various transition metals, enhancing their reactivity in catalytic processes, particularly in hydrogenation and cross-coupling reactions. The compound is typically a white to off-white solid at room temperature and is soluble in organic solvents such as dichloromethane and toluene. Its structure contributes to its steric and electronic properties, making it a valuable ligand in the synthesis of metal complexes. Additionally, DPPE can exhibit different coordination modes depending on the metal center, influencing the overall geometry and reactivity of the resulting complexes. Safety precautions should be taken when handling DPPE, as it may pose health risks if ingested or inhaled.

Formula: C₂₆H₂₄P₂

InChI: InChI=1S/C26H24P2/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)21-22-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h1-20H,21-22H2

InChI key: InChIKey=QFMZQPDHXULLKC-UHFFFAOYSA-N

SMILES: P(CCP(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4

Synonyms:

• 1,1′-(1,2-Ethanediyl)bis[1,1-diphenylphosphine]
• 1,2-Bis(Diphenylphosphor) Ethane
• 1,2-Bis(diphenylphosphanyl)ethane
• 1,2-Ethanediylbis(diphenylphosphine)
• 1,2-Ethylenebis(diphenyl)phosphine
• 1,2-Ethylenebis(diphenylphosphine)
• 2-Diphenylphosphanylethyl(diphenyl)phosphane
• B 1137
• Bis(1,2-Difenilfosfino)Etano
• Bis(1,2-Diphenylphosphino)Ethane
• Bis(1,2-diphenylphosphino)ethan
• Bis(diphenylphosphino)ethane
• DPE
• DPPE (ligand)
• Diphos
• Dppe
• Ethane-1,1-Diylbis(Diphenylphosphane)
• Ethane-1,2-Diylbis(Diphenylphosphane)
• Ethanediylbis(diphenylphosphine)
• Ethylenebis(diphenylphosphine)
• Nsc 76285
• P,P'-Ethylenebis(diphenylphosphine)
• Phosphine, 1,1'-(1,2-ethanediyl)bis[1,1-diphenyl-
• Phosphine, 1,2-ethanediylbis[diphenyl-
• Phosphine, ethylenebis[diphenyl-
• [2-(Diphenylphosphanyl)ethyl]diphenylphosphane

1,2-Bis(diphenylphosphino)ethane

CAS: 1663-45-2

Formula: C₂₆H₂₄P₂

Purity: >97.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 398.43

Ref: 3B-B1137

1,2-Bis(diphenylphosphino)ethane, 97+%, Thermo Scientific Chemicals

CAS: 1663-45-2

1,2-Bis(diphenylphosphino)ethane is a bidendate ligand used in coordination chemistry to prepare metal complexes. It is involved in the metal-catalyzed allylic alkylation and decarboxylation of allylic esters. It is also used in 1,3-diene synthesis. Further, it is used in cycloaddition reactions and carbonylation reactions. In addition to this, it is used to prepare bis(dicyclohexylphosphino)ethane by hydrogenation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Formula: C₂₆H₂₄P₂

Purity: 97+%

Molecular weight: 398.43

Ref: 02-A11419

Phosphine, 1,1'-(1,2-ethanediyl)bis[1,1-diphenyl-

CAS: 1663-45-2

Formula: C₂₆H₂₄P₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 398.4163

Ref: IN-DA001WMI

1,2-Bis(diphenylphosphino)ethane

CAS: 1663-45-2

1,2-Bis(diphenylphosphino)ethane

Formula: C₂₆H₂₄P₂

Purity: 97%

Color and Shape: white crystalline solid

Molecular weight: 398.41628g/mol

Ref: 54-OR315704

1,2-Bis(diphenylphosphino)ethane

CAS: 1663-45-2

Formula: C₂₆H₂₄P₂

Purity: 95.00%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 398.426

Ref: 10-F050106

1,2-Bis(diphenylphosphino)ethane

CAS: 1663-45-2

Formula: C₂₆H₂₄P₂

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 398.42

Ref: 7W-GK6651

1,2-Bis(diphenylphosphino)ethane

CAS: 1663-45-2

1,2-Bis(diphenylphosphino)ethane is a ligand that binds to the metal molybdenum. It has been shown to have biochemical properties in relation to its ability to form complexes with adriamycin and other drugs. The redox potential of 1,2-Bis(diphenylphosphino)ethane depends on the presence of sodium ions. This ligand is able to bind to the iron in the mitochondrial membrane and can affect the mitochondrial membrane potential. X-ray crystal structures show that this ligand binds to a monosodium salt. 1,2-Bis(diphenylphosphino)ethane has been shown to be a potent inhibitor of transfer reactions and is used as an analytical reagent for structural analysis.

Formula: C₂₆H₂₄P₂

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 398.42 g/mol

Ref: 3D-FB14158

DPPE (1,2-Bis(Diphenylphosphino)Ethane) extrapure, 98%

CAS: 1663-45-2

Formula: C₂₆H₂₄P₂

Purity: min.98%

Color and Shape: White to off-white, Powder

Molecular weight: 398.4

Ref: SR-48237

1,​2-​Bis(diphenylphosphin​o)​ethane

Controlled Product

CAS: 1663-45-2

Applications: 1,​2-​Bis(diphenylphosphin​o)​ethane is a chiral ligand used in organic synthesis in the hydroboration and cyclization of 1,6-enynes with pinacolborane.
References Yu, S. et al.: J. Am. Chem. Soc., 139, 6526 (2017);

Formula: C₂₆H₂₄P₂

Color and Shape: Neat

Molecular weight: 398.42

Ref: TR-B430430