CAS 166403-66-3

rac-Tenofovir Diphosphate-d6

CAS: 166403-66-3

Formula: C₉H₁₀D₆N₅O₁₀P₃

Molecular weight: 453.21

Ref: 4Z-T-02200

Tenofovir Diphosphate

CAS: 166403-66-3

Formula: C₉H₁₆N₅O₁₀P₃

Molecular weight: 447.17

Ref: 4Z-T-025

rac Tenofovir-d6 Diphosphate Triethylamine Salt (mixture of diastereomers)

Controlled Product

CAS: 166403-66-3

Stability Very Hygroscopic
Applications rac Tenofovir-d6 Diphosphate Triethylamine Salt is an isotopic analog of Tenofovir Diphosphate Triethylamine Salt (T018525), which is a metabolite of Tenofovir (T018500).
References Hazra, R., et al.: Antimicrob. Agents Chemother., 48, 124 (2004), Piketty, C., et al.: Antivir. Ther., 11, 213 (2006), Molto, J., et al.: Ther. Drug Monit., 29, 648 (2007),

Formula: C₉H₁₀D₆N₅O₁₀P₃•x(C₆H₁₅N)

Color and Shape: Neat

Molecular weight: 453.21+x(101.19)

Ref: TR-T018527

Tenofovir diphosphate triethylamine(mixture of diastereomers)

CAS: 166403-66-3

Tenofovir diphosphate triethylamine (mixture of diastereomers) is an antiviral compound, which is a synthetic chemical product derived from the parent compound, tenofovir. This formulation includes a mixture of diastereomers to enhance its solubility and bioavailability. The compound primarily functions as a nucleotide reverse transcriptase inhibitor (NRTI). It targets viral reverse transcriptase enzymes, inhibiting DNA synthesis and subsequent viral replication by causing premature chain termination.

Formula: C₉H₁₆N₅O₁₀P₃•(C₆H₁₅N)x

Purity: Min. 95%

Ref: 3D-AT183486

Tenofovir diphosphate

CAS: 166403-66-3

Tenofovir diphosphate is an antiviral compound, which is a key active metabolite derived from the prodrugs tenofovir disoproxil fumarate and tenofovir alafenamide, both originating from chemical synthesis. Its mode of action involves inhibiting the activity of HIV-1 reverse transcriptase by competing with the natural substrate, deoxyadenosine 5’-triphosphate, and causing chain termination after incorporation into viral DNA. This mechanism effectively prevents the replication of retroviral DNA, thus halting the progression of the infection.

Formula: C₉H₁₆N₅O₁₀P₃

Purity: Min. 95%

Molecular weight: 447.17 g/mol

Ref: 3D-FT162482

Tenofovir diphosphate

CAS: 166403-66-3

TFV-DP inhibits DNA polymerases, mimics dATP, and is used by HIV-1's reverse transcriptase.

Formula: C₉H₁₆N₅O₁₀P₃

Color and Shape: Solid

Molecular weight: 447.17

Ref: TM-T37909

Tenofovir Diphosphate

CAS: 166403-66-3

Formula: C₉H₁₆N₅O₁₀P₃

Molecular weight: 447.18

Ref: ST-EA-CP-T5081