CAS 16679-58-6

Desmopressin

Description:

Desmopressin is a synthetic analog of vasopressin, a naturally occurring hormone that regulates water retention in the body. It is primarily used in the treatment of conditions such as diabetes insipidus and bedwetting (nocturnal enuresis). Desmopressin exhibits a high affinity for the V2 vasopressin receptors, which are primarily located in the kidneys, leading to increased water reabsorption and reduced urine output. The substance is characterized by its ability to enhance the concentration of urine without significantly affecting blood pressure, making it a preferred choice for patients with specific medical needs. Desmopressin is typically administered in various forms, including nasal spray, oral tablets, and injectable solutions. Its pharmacokinetics indicate a relatively long half-life compared to natural vasopressin, allowing for less frequent dosing. Additionally, desmopressin is generally well-tolerated, although potential side effects may include headache, nausea, and, in rare cases, water retention leading to hyponatremia. Overall, desmopressin is a valuable therapeutic agent in managing certain disorders related to water balance in the body.

Formula: C₄₆H₆₄N₁₄O₁₂S₂

InChI: InChI=1/C46H64N14O12S2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52)/t28-,29+,30+,31+,32+,33+,34+/m1/s1

Synonyms:

• 1-(3-Mercaptopropanoic acid)-8-D-argininevasopressin
• 1-{[(4R,7S,10S,13S,16S)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-arginylglycinamide
• 16679-58-6
• 240-726-7
• glycinamide, 1-[[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-arginyl-
• Octostim
• 1-{[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-N~5~-(diaminomethylidene)-D-ornithylglycinamide
• (1-Deamino-8-D-Arg)-vasopressin
• [1-β-Mercaptopropionic acid-8-D-arginine]vasopressin
• [Deamino1-D-arginine8]vasopressin
• [Desamino-Cys1,D-Arg8]vasopressin
• 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin
• 1: PN: US20020013262 PAGE: 2 claimed protein
• 1-Deamino-[8-D-arginine]vasopressin
• 1-Deamino-1-[D-Arg8]-vasopressin
• 1-Desamino-8-D-arginine-vasopressin
• 1-Desaminocystine-8-D-arginine-vasopressin
• 45: PN: WO2005000360 SEQID: 40 claimed protein
• 8-D-Arginine deaminovasopressin
• Adiuretin
• Adiuretin SD
• DAV Ritter
• Ddavp
• Desmopresina
• Desmopressine
• Desmospray
• Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-D-arginyl-, cyclic (1→5)-disulfide
• Minirin
• Minrin
• Peptide, (Xaa-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly), ?
• Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-
• Vasopressin, 1-(3-mercaptopropionic acid)-8-D-arginine-
• (Deamino-Cys1,D-Arg8)-Vasopressin acetate salt
• 3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-D-Arg-Gly-NH2 acetate salt (Disulfide bond)
• [DEAMINO1, DARG8] VASOPRESSIN
• [deamino-cys1, d-arg8]-vasopressin acetate hydrate
• [deamino-Cys
• DESMOPRESSIN, HUMAN
• MPR-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• [Deamino1,DArg8] Vasopressin (dDAVP) Desmopressin
• 3-MERCAPTOPROPIONYL-YFQNCPRG (DISULFIDE BRIDGE: 1-6)
• DESMOPRESSIN
• M.W. 1069.22 C46H64N14O12S2
• MAP-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• 3-Mercapto(1)propionyl-L-Tyr-L-Phe-L-Gln-L-Asn-L-Cys(1)-L-Pro-D-Arg-Gly-NH2
• 3-MERCAPTOPROPIONYL-TYR-PHE-GLN-ASN-CYS-PRO-D-ARG-GLY-NH2
• DDAVP, HUMAN
• DESMOPRESSIN ACETATE PH. EUR.
• DESAMINO-[D-ARG8]VASOPRESSIN
• [DEAMINO-CYS1, D-ARG8]-VASOPRESSIN

(Deamino-Cys¹,D-Arg⁸)-Vasopressin

CAS: 16679-58-6

Desmopressin (DDAVP), as the first vasopressin analog with a very high and very specific antidiuretic effect, has been widely used for different therapeutic purposes. DDAVP also improves human learning and memory processes. CAS Number (desmopressin acetate): 62288-83-9.

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purity: 99.7%

Color and Shape: White Powder

Molecular weight: 1069.23

Ref: 01-4012273

Desmopressin

CAS: 16679-58-6

Desmopressin

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Color and Shape: Off White Solid

Molecular weight: 1068.42696

Ref: 47-381

Desmopressin impurity standard

CAS: 16679-58-6

Desmopressin impurity standard

Color and Shape: Off-White

Ref: 47-1188

Desmopressin Trifluoroacetate

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂·C₂HF₃O₂

Color and Shape: Off-White Solid

Molecular weight: 1069.24 114.02

Ref: 4Z-PD-8212

Desmopressin

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Color and Shape: White To Off-White Solid

Molecular weight: 1069.22

Ref: 4Z-PD-821

Desmopressin Acetate

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1069.22

Ref: BP-BPPG021

Asp(5)-Desmopressin Acetate Salt

Controlled Product

CAS: 16679-58-6

Formula: C₄₈H₆₈N₁₄O₁₄S₂

Color and Shape: Off-White

Molecular weight: 1129.27

Ref: TR-A788625

(D-Asn)-Desmopressin

Controlled Product

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂·x(C₂H₄O₂)

Color and Shape: Neat

Molecular weight: 1069.22 + x(60.05)

Ref: TR-A788858

Desmopressin

Controlled Product

CAS: 16679-58-6

Desmopressin is a synthetic analog of the natural hormone arginine vasopressin. It has been shown to be effective in the treatment of primary nocturnal enuresis, and a number of studies have reported that desmopressin is an effective therapy for idiopathic nocturnal enuresis. Desmopressin also has effects on water permeability, hemolysis, and protein synthesis. It increases the concentration of camp levels in urine and plasma while also inhibiting erythrocyte aggregation. Desmopressin has been shown to be more effective than placebo in women with primary nocturnal enuresis.

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,069.22 g/mol

Ref: 3D-FD110210

Desmopressin

CAS: 16679-58-6

Formula: C₄₆H₆₄N₁₄O₁₂S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 1069.2170

Ref: IN-DA019FVJ