CAS 1668-19-5

Doxepin

Description:

Doxepin is a tricyclic antidepressant primarily used to treat depression and anxiety disorders, as well as insomnia. Its chemical structure features a dibenzoxepin core, which contributes to its pharmacological properties. Doxepin acts by inhibiting the reuptake of norepinephrine and serotonin, thereby enhancing mood and alleviating anxiety. It also possesses antihistaminic properties, making it effective for treating allergic reactions and sleep disturbances. The substance is typically administered in oral form and is known for its relatively long half-life, which allows for once-daily dosing in many cases. Doxepin can cause side effects, including sedation, dry mouth, and weight gain, and it may interact with other medications, necessitating careful management by healthcare providers. Its safety profile and efficacy have made it a valuable option in psychiatric and sleep medicine, although it is essential to monitor patients for potential adverse effects, especially in the elderly or those with pre-existing health conditions.

Formula: C₁₉H₂₁NO

InChI: InChI=1/C19H21NO/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3/p+1/b17-11-

InChI key: InChIKey=ODQWQRRAPPTVAG-UHFFFAOYSA-N

SMILES: C(CCN(C)C)=C1C=2C(COC=3C1=CC=CC3)=CC=CC2

Synonyms:

• (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine
• (3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-aminium
• 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-
• 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepin
• 11-[3-(Dimethylamino)propylidene]-6H-dibenz[b,e]oxepin
• 3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine
• 3-Dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine
• Dibenz[b,e]oxepin, 1-propanamine deriv.
• Dibenz[b,e]oxepin-Δ11(6H),γ-propylamine, N,N-dimethyl-
• Dibenz[b,e]oxepin-Δ¹¹⁽⁶^H^),γ-propylamine, N,N-dimethyl-
• Doxepine
• N,N-Dimethyldibenz[b,e]oxepin-Δ11(6H),γ-propylamine
• N,N-Dimethyldibenz[b,e]oxepin-Δ¹¹⁽⁶^H^),γ-propylamine
• Nsc 108160
• Curatin
• e)oxepin-delta(11(6h),gamma)-propylamine,n,n-dimethyl-dibenz(
• ,gamma-propylamine, N,N-dimethyl-
• 3-Dibenz[b,e]oxepin-(6H)-ylidene-N,N-dimethyl-1-propanamine
• Quitaxon
• P-3693A
• p3693a
• N,N-Dimethyl-3-(6,11-dihydrodibenz[b,e]oxepin-11-ylidene)propylamine
• Dibenz(b,e)oxepin-delta
• 3-dibenz(b,e)oxepin-11(6h)-ylidene-n,n-dimethyl-1-propanamin
• n,n-dimethyldibenz(b,e)oxepin-delta(11(6h),gamma)-propylamine
• 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz(b,e)oxipin
• Docepin
• 11-(3-dimethylamino-propyliden)-6,11-dihydro-dibenz(b,e)oxipin
• 1-Propanamine, 3-dibenzb,eoxepin-11(6H)-ylidene-N,N-dimethyl-
• (3Z)-3-Dibenzo[b,E]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine
• 11-(3-(dimethylamino)propylidene)-6h-dibenz(b,e)0xepine
• Aponal
• 11(6H)

Doxepin Hydrochloride (mixture of isomers)

CAS: 1229-29-4, 1668-19-5

Formula: C₁₉H₂₁NO·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 315.84

Ref: 3B-D4626

1-PROPANAMINE, 3-DIBENZ[B,E]OXEPIN-11(6H)-YLIDENE-N,N-DIMETHYL-

CAS: 1668-19-5

Formula: C₁₉H₂₁NO

Purity: >98%

Color and Shape: Solid

Molecular weight: 279.3761

Ref: IN-DA001WYP

Doxepin

CAS: 1668-19-5

Formula: C₁₉H₂₁NO

Molecular weight: 279.38

Ref: 7W-GP9511

Doxepin

CAS: 1668-19-5

Doxepin: tricyclic antidepressant, inhibits serotonin/norepinephrine reuptake, helps atopic dermatitis/urticaria, cognitive protector, anti-inflammatory.

Formula: C₁₉H₂₁NO

Color and Shape: Solid

Molecular weight: 279.38

Ref: TM-T60521