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CAS 1668-85-5

:

(-)-Epigalanthamine

Description:
(-)-Epigalanthamine, with the CAS number 1668-85-5, is a naturally occurring alkaloid primarily derived from various plant species, particularly those in the Amaryllidaceae family. This compound is known for its structural similarity to galantamine, which is a well-known acetylcholinesterase inhibitor. (-)-Epigalanthamine exhibits a chiral center, resulting in its specific optical activity, which is significant in pharmacological contexts. The substance is characterized by its ability to enhance cholinergic neurotransmission, making it of interest in the study of neurodegenerative diseases such as Alzheimer's. Additionally, it possesses potential neuroprotective properties and may influence cognitive function. The compound is typically found in low concentrations in plant sources, necessitating extraction and purification for research and therapeutic applications. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are areas of ongoing research, as understanding these properties is crucial for its potential use in clinical settings. Overall, (-)-Epigalanthamine represents a promising area of study in medicinal chemistry and neuropharmacology.
Formula:C17H21NO3
InChI:InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14+,17+/m1/s1
InChI key:InChIKey=ASUTZQLVASHGKV-IFIJOSMWSA-N
SMILES:O(C)C1=C2C=3[C@]4([C@@](O2)(C[C@H](O)C=C4)[H])CCN(C)CC3C=C1
Synonyms:
  • (-)-Epigalanthamine
  • (3Alpha)-Galanthamine
  • (4aS,6S,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol
  • 2-Epigalanthamine
  • 2-epi-Galanthamine
  • 3-Epigalanthamine
  • 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, (4aS,6S,8aS)-
  • 6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, [4aS-(4aα,6α,8aR*)]-
  • Epigalantamine
  • Galanthamine, (3α)-
  • Sph 1068
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