CAS 16680-47-0

Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt

Description:

Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt, commonly referred to as sodium sulfoestrone, is a synthetic derivative of estrone, a naturally occurring estrogen. This compound features a steroid backbone with a sulfooxy group at the 3-position, which enhances its solubility in water and biological fluids, making it more bioavailable. The presence of the sulfonate group contributes to its ionic nature, allowing it to interact with various biological systems, particularly in hormone-related pathways. Sodium sulfoestrone is often utilized in research and clinical settings to study estrogenic activity and its effects on various physiological processes. Its structural characteristics include multiple double bonds within the steroid framework, which are crucial for its biological activity. The compound is typically administered in a sodium salt form to improve stability and solubility. As with many steroid derivatives, it may exhibit specific pharmacological effects, including potential applications in hormone replacement therapy and other therapeutic areas related to estrogen modulation.

Formula: C₁₈H₁₉NaO₅S

InChI: InChI=1/C18H20O5S.Na/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;/h3-5,10,14,16H,2,6-9H2,1H3,(H,20,21,22);/q;+1/t14-,16+,18+;/m1./s1

InChI key: InChIKey=RMFRALSRVMTLBI-QWAPEVOJSA-N

SMILES: C[C@@]12[C@](C=3[C@@](C=4C(CC3)=CC(OS(=O)(=O)O)=CC4)(CC1)[H])(CCC2=O)[H].[Na]

Synonyms:

• 17-Oxoestra-1,3,5(10),7-Tetraen-3-Yl Hydrogen Sulfate
• 17-Oxoestra-1,3,5(10),7-tetraen-3-yl sodium sulfate
• Conjugated estrogens: sodium equilin sulfate
• Equilin sodium sulfate
• Equilin, sulfate, sodium salt
• Equilin, sulfate, sodium salt (6CI)
• Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt (1:1)
• Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy-, hydrogen sulfate sodium salt (8CI)
• Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy-, hydrogen sulfate, sodium salt
• Sodium 17-Oxoestra-1,3,5(10),7-Tetraen-3-Yl Sulfate
• Sodium equilin 3-monosulfate
• Sodium equilin sulfate
• Unii-7Xy8Fw3E68
• Estra-1,3,5(10),7-tetraen-17-one, 3-(sulfooxy)-, sodium salt
• C13416
• 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one Hydrogen Sulfate SodiuM Salt
• Equilin 3-Sulfate Sodium Salt
• 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one SodiuM Salt
• 3-(Sodiosulfooxy)-1,3,5(10),7-estratetren-17-one
• SODIUMEQUILINESULPHATE
• SODIUMEQUILINSULPHATE
• Equilin 3-Sulfate SodiuM Salt (Discontinued, see E592825)
• Equilin 3-Sulfate SodiuM Salt (Stabilized with TRIS, 50% w/w)

Equilin 3-Sulfate Sodium Salt

CAS: 16680-47-0

Formula: C₁₈H₁₉O₅S·Na

Color and Shape: Off-White Solid

Molecular weight: 347.41 22.99

Ref: 4Z-E-305

Equilin 3-Sulfate Sodium Salt (Stabilized with TRIS, 50% w/w)

Controlled Product

CAS: 16680-47-0

Stability Hygroscopic
Applications Equilin 3-Sulfate Sodium Salt, is a metabolite of Equilin (E592800).
References Hajdu, A., et al.: Experientia, 27, 956 (1971), Adams, W.P., et al.: J. Pharma. Sci., 68, 986 (1979),

Formula: C₁₈H₁₉O₅S·Na

Color and Shape: Neat

Molecular weight: 370.4

Ref: TR-E592825

Equilin 3-Sulfate Sodium Salt

CAS: 16680-47-0

Formula: C₁₈H₁₉O₅SNa

Molecular weight: 347.4:23.0

Ref: ST-EA-CP-E26001