CAS 166882-70-8

2H-Indol-2-one,1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]-

Description:

2H-Indol-2-one, 1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]- is a complex organic compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This particular compound features a dihydroindole moiety, indicating the presence of additional hydrogen atoms that contribute to its stability and reactivity. The presence of a thienyl group suggests potential for aromatic interactions, while the tetrahydro-4-hydroxy-2-methyl-2H-pyran moiety introduces a chiral center, which may influence its biological activity and interactions. The compound's molecular structure indicates potential for various functional groups, which can participate in hydrogen bonding and other intermolecular interactions. Such characteristics may render it of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to the potential for diverse biological activities stemming from its unique structural features.

Formula: C₁₉H₂₁NO₃S₂

Synonyms:

• 2H-Indol-2-one,1,3-dihydro-1-methyl-5-[[4-(tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl)-2-thienyl]thio]-,(2S-trans)-
• Zd 4407

2H-Indol-2-one, 1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]-

CAS: 166882-70-8

Formula: C₁₉H₂₁NO₃S₂

Molecular weight: 375.5049

Ref: IN-DA001WZ6

AZD 4407

CAS: 166882-70-8

AZD 4407 is a potent, selective inhibitor of the protein kinase C (PKC) family with IC50 values in the low nanomolar range. It inhibits PKC isoforms α, βI and γ with IC50 values of 0.5 nM, 1 nM and 3 nM respectively. AZD 4407 is a cell permeable inhibitor that does not inhibit other kinases such as protein kinase A or CDKs.
AZD 4407 can be used as a research tool for PKC-mediated signal transduction pathways in cells, tissues and organisms. It can also be used to study PKC-dependent regulation of ion channels, antibody production or receptor activation by peptides.

Formula: C₁₉H₂₁NO₃S₂

Purity: Min. 95%

Molecular weight: 375.5 g/mol

Ref: 3D-RGA88270

AZD 4407

CAS: 166882-70-8

AZD 4407 is a potent inhibitor of 5-lipoxygenase.

Formula: C₁₉H₂₁NO₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 375.5

Ref: TM-T10438