CAS 166978-46-7

7-BROMO-4,4-DIMETHYL-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE

Description:

7-Bromo-4,4-dimethyl-3,4-dihydro-2H-naphthalen-1-one is an organic compound characterized by its naphthalene structure, which features a bromine substituent and two methyl groups. This compound belongs to the class of ketones, specifically a substituted naphthalenone, indicating the presence of a carbonyl group (C=O) within its structure. The bromine atom introduces notable reactivity, making it a potential candidate for various chemical transformations, including nucleophilic substitutions. The dimethyl groups contribute to the compound's steric bulk, which can influence its reactivity and interactions with other molecules. In terms of physical properties, compounds of this type typically exhibit moderate solubility in organic solvents and may have distinct melting and boiling points influenced by their molecular structure. The presence of the bromine atom and the ketone functional group can also affect the compound's spectral characteristics, making it identifiable through techniques such as NMR and IR spectroscopy. Overall, this compound may have applications in organic synthesis and medicinal chemistry, particularly in the development of brominated derivatives.

Formula: C₁₂H₁₃BrO

InChI: InChI=1/C12H13BrO/c1-12(2)6-5-11(14)9-7-8(13)3-4-10(9)12/h3-4,7H,5-6H2,1-2H3

SMILES: CC1(C)CCC(=O)c2cc(ccc12)Br

Synonyms:

• 7-Bromo-4,4-dimethyl-1-tetralone
• 7-bromo-4,4-dimethyl-3,4-dihydronaphthalen-1(2H)-one

1(2H)-Naphthalenone, 7-bromo-3,4-dihydro-4,4-dimethyl-

CAS: 166978-46-7

Formula: C₁₂H₁₃BrO

Purity: 96%

Color and Shape: Solid

Molecular weight: 253.1350

Ref: IN-DA001X2A

7-Bromo-4,4-dimethyl-3,4-dihydronaphthalen-1(2H)-one

CAS: 166978-46-7

7-Bromo-4,4-dimethyl-3,4-dihydronaphthalen-1(2H)-one

Purity: 99%

Molecular weight: 253.14g/mol

Ref: 54-OR77899

7-BROMO-4,4-DIMETHYL-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE

CAS: 166978-46-7

Formula: C₁₂H₁₃BrO

Purity: 96%

Color and Shape: Solid

Molecular weight: 253.139

Ref: 10-F302873

7-Bromo-4,4-dimethyl-1-tetralone

Controlled Product

CAS: 166978-46-7

Applications Intermediate in the production of high affinity retinoic acid receptor (RAR) antagonists.
References Vuligonda, V., et al.: Bioorg. Med. Chem. Lett., 9, 743 (1999), Johnson, A., et al.: Bioorg. Med. Chem. Lett., 9, 573 (1999),

Formula: C₁₂H₁₃BrO

Color and Shape: Neat

Molecular weight: 253.14

Ref: TR-B684185

7-Bromo-4,4-dimethyl-1-tetralone

CAS: 166978-46-7

7-Bromo-4,4-dimethyl-1-tetralone is a retinoic acid receptor agonist that is used in the treatment of psoriasis. 7-Bromo-4,4-dimethyl-1-tetralone binds to the retinoic acid receptor and activates it. It also inhibits epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR). This drug has been shown to be effective in the treatment of psoriasis. 7-Bromo-4,4-dimethyl-1 -tetralone is an analog of retinoic acid and may have similar effects as this compound. !-- --> !-- --> !-- --> !-- --> -->

Formula: C₁₂H₁₃BrO

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 253.14 g/mol

Ref: 3D-FB19135