CAS 167015-23-8

Fmoc-Homocys(Trt)-OH

Description:

Fmoc-Homocys(Trt)-OH, with the CAS number 167015-23-8, is a chemical compound commonly used in peptide synthesis and research. It is a derivative of homocysteine, an amino acid that plays a crucial role in various biological processes. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide synthesis. The Trt (trityl) group protects the thiol side chain of homocysteine, preventing unwanted reactions while facilitating the formation of peptide bonds. This compound is typically utilized in solid-phase peptide synthesis, where the stability of the protecting groups is essential for the successful assembly of peptides. Fmoc-Homocys(Trt)-OH is characterized by its ability to undergo deprotection under mild conditions, making it suitable for sequential synthesis steps. Its structural features contribute to its utility in the development of peptides with specific biological activities, including those relevant in medicinal chemistry and drug development. Overall, this compound is significant in the field of synthetic organic chemistry and biochemistry.

Formula: C₃₈H₃₃NO₄S

Synonyms:

• Fmoc-HoCys(Trt)-OH

Fmoc-Homocys(Trt)-OH

CAS: 167015-23-8

Educt for the synthesis of β-turn peptidomimetics (Jiang and Burgess). Lindman et al. obtained Hcy-containing angiotensin II analogs by Fmoc-SPPS. Homocysteine can function as thiol component during chemical ligation. S-Methylation of the resulting peptide yields methionine.

Formula: C₃₈H₃₃NO₄S

Purity: 98.0%

Color and Shape: Yellowish Powder

Molecular weight: 599.75

Ref: 01-4025118

Fmoc-HoCys(Trt)-OH

CAS: 167015-23-8

Formula: C₃₈H₃₃NO₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 599.7379

Ref: IN-DA007WC3

S-Trityl-L-homocycteine, N-FMOC protected

CAS: 167015-23-8

S-Trityl-L-homocycteine, N-FMOC protected

Purity: 99%

Molecular weight: 599.74g/mol

Ref: 54-OR2635

Fmoc-S-trityl-L-homocysteine

CAS: 167015-23-8

Fmoc-S-trityl-L-homocysteine is a positron analog that can be used for the diagnosis of cancer. It is labeled with carbon-11, fluorine-18, or nitrogen-13 and can be identified by PET scanning. Fmoc-S-trityl-L-homocysteine has been shown to exhibit epidermal growth factor activity in vitro and in vivo models. This compound also helps in the diagnosis of cancer, as it binds to the surface of tumor cells and increases uptake by these cells. Fmoc-S-trityl-L-homocysteine is a congener of epidermal growth factor that may be used as a model system for other growth factors.

Formula: C₃₈H₃₃NO₄S

Purity: Min. 97 Area-%

Color and Shape: Off-White Powder

Molecular weight: 599.74 g/mol

Ref: 3D-FF48586

Fmoc-L-HomoCys(Trt)-OH

CAS: 167015-23-8

Formula: C₃₈H₃₃NO₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 599.75

Ref: 10-F340578