CAS 167073-19-0
:Pitavastatin Ethyl Ester
Description:
Pitavastatin ethyl ester is a synthetic compound belonging to the statin class of drugs, primarily used for lowering cholesterol levels in the blood. It is an ester derivative of pitavastatin, which is known for its ability to inhibit HMG-CoA reductase, an enzyme crucial in the cholesterol biosynthesis pathway. The compound typically appears as a white to off-white solid and is characterized by its moderate solubility in organic solvents and limited solubility in water. Its molecular structure includes a lactone ring and a hydroxy group, contributing to its pharmacological activity. Pitavastatin ethyl ester is often studied for its potential benefits in managing dyslipidemia and reducing cardiovascular risk. Additionally, it may exhibit antioxidant properties and influence lipid metabolism. As with other statins, its use may be associated with side effects, including muscle pain and liver enzyme alterations, necessitating monitoring during therapy. Overall, pitavastatin ethyl ester represents a significant advancement in lipid-lowering therapies, with ongoing research into its broader health implications.
Formula:C11H23Cl2N2O2PS
InChI:InChI=1/C11H23Cl2N2O2PS/c1-3-10-19-11-4-9-17-18(16,14(11)2)15(7-5-12)8-6-13/h11H,3-10H2,1-2H3
SMILES:CCCSC1CCOP(=O)(N1C)N(CCCl)CCCl
Synonyms:- 2H-1,3,2-oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-3-methyl-4-(propylthio)-, 2-oxide
- N,N-bis(2-chloroethyl)-3-methyl-4-(propylsulfanyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
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