CAS 16710-13-7

6-methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione

Description:

6-Methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione, with the CAS number 16710-13-7, is a chemical compound that belongs to the class of pyrimidine derivatives. This substance features a pyrimidine ring, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. The presence of a furanosyl group indicates that it has a five-membered sugar-like structure, contributing to its potential biological activity. The methyl group at the 6-position of the pyrimidine ring suggests that it may exhibit specific steric and electronic properties, influencing its reactivity and interactions with biological targets. As a diketone, it contains two carbonyl groups, which can participate in various chemical reactions, including condensation and nucleophilic addition. This compound may have applications in medicinal chemistry, particularly in the development of nucleoside analogs or other bioactive molecules. However, detailed studies on its pharmacological properties and mechanisms of action would be necessary to fully understand its potential uses.

Formula: C₁₀H₁₄N₂O₆

InChI: InChI=1/C10H14N2O6/c1-4-2-6(14)11-10(17)12(4)9-8(16)7(15)5(3-13)18-9/h2,5,7-9,13,15-16H,3H2,1H3,(H,11,14,17)

SMILES: Cc1cc(nc(=O)n1C1C(C(C(CO)O1)O)O)O

6-Methyluridine

CAS: 16710-13-7

Formula: C₁₀H₁₄N₂O₆

Molecular weight: 258.2280

Ref: IN-DA001X4E

6-Methyluridine

CAS: 16710-13-7

6-Methyluridine

Purity: 98%

Ref: 54-OR1042366

6-Methyluridine

CAS: 16710-13-7

Ref: 7W-GN5347

6-Methyluridine

CAS: 16710-13-7

Nucleosides and Reagents - 6-Modified pyrimidine nucleoside

Formula: C₁₀H₁₄N₂O₆

Color and Shape: Solid

Molecular weight: 258.23

Ref: TM-TNU0134

6-Methyluridine

Controlled Product

CAS: 16710-13-7

Applications 6-Methyluridine exhibited weak antimalarial activity against P. falciparum 3D7 isolate. It is a weak substrate of Escherichia coli pyrimidine nucleoside phosphorylase.
References Bello, A., et al.: J. Med. Chem., 51, 439 (2008); Felczak, K., et al.: J. Med. Chem., 39, 1720 (1996)

Formula: C₁₀H₁₄N₂O₆

Color and Shape: Neat

Molecular weight: 258.23

Ref: TR-M338165

6-Methyluridine

CAS: 16710-13-7

Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.

Formula: C₁₀H₁₄N₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 258.23 g/mol

Ref: 3D-NM08576