CAS 1672-76-0

Chlorpromazine N-oxide

Description:

Chlorpromazine N-oxide is a derivative of chlorpromazine, which is an antipsychotic medication commonly used to treat various mental health disorders. The N-oxide form indicates the presence of an oxygen atom bonded to the nitrogen atom in the side chain of the chlorpromazine molecule. This modification can influence the compound's pharmacological properties, including its solubility and biological activity. Chlorpromazine N-oxide is typically characterized by its white to off-white crystalline appearance and is soluble in polar solvents. It retains some of the therapeutic effects of chlorpromazine, but its specific activity and side effect profile may differ. The compound's molecular structure includes a tricyclic system, which is common among antipsychotic agents, and it may exhibit interactions with neurotransmitter receptors, particularly dopamine and serotonin receptors. As with many pharmaceutical compounds, safety and efficacy are paramount, and any use of chlorpromazine N-oxide should be guided by clinical research and regulatory standards.

Formula: C₁₇H₁₉ClN₂OS

InChI: InChI=1S/C17H19ClN2OS/c1-20(2,21)11-5-10-19-14-6-3-4-7-16(14)22-17-9-8-13(18)12-15(17)19/h3-4,6-9,12H,5,10-11H2,1-2H3

InChI key: InChIKey=LFDFWIIFGRXCFR-UHFFFAOYSA-N

SMILES: C(CCN(C)(C)=O)N1C=2C(SC=3C1=CC=CC3)=CC=C(Cl)C2

Synonyms:

• 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, N-oxide
• 3-(2-chloro-10-oxido-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
• Ba 2836
• Chlorpromazin N-oxide
• Chlorpromazine oxide
• Phenothiazine, 2-chloro-10-[3-(dimethylamino)propyl]-, N-oxide
• [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine oxide
• Chlorpromazine N-oxide

10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, N-oxide

CAS: 1672-76-0

Formula: C₁₇H₁₉ClN₂OS

Color and Shape: Solid

Molecular weight: 334.8636

Ref: IN-DA001X7J

Chlorpromazine N-Oxide

CAS: 1672-76-0

Formula: C₁₇H₁₉ClN₂OS

Color and Shape: White To Off-White Solid

Molecular weight: 334.86

Ref: 4Z-C-125005

Chlorpromazine N-Oxide

Controlled Product

CAS: 1672-76-0

Stability Hygroscopic
Applications Chlorpromazine N-Oxide is a metabolite of Chlorpromazine. Chlorpromazine exhibits antiadrenergic, antiserotonergic, anticholinergic, and antihistaminergic properties, and commonly used to treat schizophrenia.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, Z., et al.: Handbook of Metabolic Pathways of Xenobiotics, 3, 1102 (2014); Kigondu, E. M., et al.: MedChemComm, 5, 502 (2014); Yeung, P. K. F., et al.: Eur. J. Clin. Pharmacol., 45, 563 (1993)

Formula: C₁₇H₁₉ClN₂OS

Color and Shape: Neat

Molecular weight: 334.86

Ref: TR-C596430

Chlorpromazine N-Oxide impurity

CAS: 1672-76-0

Formula: C₁₇H₁₉ClN₂OS

Molecular weight: 334.86

Ref: ST-EA-CP-C19008