CAS 1672665-49-4

PT-2385

CAS: 1672665-49-4

Formula: C₁₇H₁₂F₃NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 383.3417

Ref: IN-DA00ABOZ

PT-2385

CAS: 1672665-49-4

PT-2385

Purity: ≥98%

Molecular weight: 383.34g/mol

Ref: 54-BUP12544

(S)-3-((2,2-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1H-Inden-4-Yl)Oxy)-5-Fluorobenzonitrile

CAS: 1672665-49-4

(S)-3-((2,2-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1H-Inden-4-Yl)Oxy)-5-Fluorobenzonitrile

Purity: 98%

Molecular weight: 383.34g/mol

Ref: 54-PC108432

PT-2385

CAS: 1672665-49-4

PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).

Formula: C₁₇H₁₂F₃NO₄S

Purity: 98.91% - 99.55%

Color and Shape: Solid

Molecular weight: 383.34

Ref: TM-T7848

PT2385

CAS: 1672665-49-4

PT2385 is a small molecule inhibitor, which is derived from pharmaceutical research targeting the hypoxia-inducible factor pathway. It specifically targets and inhibits hypoxia-inducible factor 2 alpha (HIF-2α), a key transcription factor involved in tumor angiogenesis and growth. The mode of action of PT2385 involves binding selectively to the PAS-B domain of HIF-2α, preventing its dimerization and subsequent DNA binding, thereby attenuating hypoxic response gene expression.

Formula: C₁₇H₁₂F₃NO₄S

Purity: Min. 95%

Molecular weight: 383.34 g/mol

Ref: 3D-XRC66549