
CAS 1672698-96-2
:Carfilzomib Impurity 4 (N-Oxide Impurity)
Description:
Carfilzomib Impurity 4, also known as N-Oxide Impurity, is a chemical compound associated with the pharmaceutical agent carfilzomib, which is used in the treatment of multiple myeloma. This impurity is characterized by the presence of an N-oxide functional group, which typically indicates the oxidation of a nitrogen atom within an amine or amide structure. The presence of this functional group can influence the compound's solubility, stability, and biological activity. Impurities like Carfilzomib Impurity 4 are important to monitor during the synthesis and formulation of pharmaceuticals, as they can affect the efficacy and safety of the final product. The CAS number 1672698-96-2 uniquely identifies this compound in chemical databases, facilitating its study and regulation. Understanding the characteristics of such impurities is crucial for quality control in drug development, ensuring that the therapeutic agents meet the required standards for purity and potency.
Formula:C40H57N5O8
Synonyms:- Carfilzomib Impurity 4 (N-Oxide Impurity)
- (αS)-2-[[2-(4-Oxido-4-Morpholinyl)acetyl]amino]Benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-Phenylalaninamide
- Carfilzomib N-Oxide Impurity
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Found 3 products.
Carfilzomib N-Oxide
CAS:Formula:C40H57N5O8Color and Shape:White To Off-White SolidMolecular weight:735.93(alphaS)-2-[[2-(4-Oxido-4-Morpholinyl)acetyl]amino]Benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-Phenylalaninamide
CAS:Controlled Product<p>Applications O846805 is a impurity of Carfilzomib (C183460), a newly approved proteasome-inhibiting anticancer drug.<br>References Sestak, V., et al.: Journal of Pharmaceutical and Biomedical Analysis 124, 365 (2016)<br></p>Formula:C40H57N5O8Color and Shape:Off-WhiteMolecular weight:735.909


