CAS 16732-57-3

Ethyl 5-nitroindole-2-carboxylate

Description:

Ethyl 5-nitroindole-2-carboxylate is a chemical compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This compound features a nitro group (-NO2) at the 5-position and an ethyl ester functional group at the 2-position of the indole ring, contributing to its reactivity and solubility properties. Ethyl 5-nitroindole-2-carboxylate is typically a yellow to orange solid, and it is known for its potential applications in organic synthesis and medicinal chemistry, particularly in the development of pharmaceuticals. The presence of the nitro group can enhance the compound's electrophilic character, making it useful in various chemical reactions, including nucleophilic substitutions and cycloadditions. Additionally, the ethyl ester moiety can be hydrolyzed to yield the corresponding carboxylic acid, expanding its utility in synthetic pathways. As with many nitro compounds, it is important to handle this substance with care due to potential toxicity and environmental considerations.

Formula: C₁₁H₁₀N₂O₄

InChI: InChI=1/C11H10N2O4/c1-2-17-11(14)10-6-7-5-8(13(15)16)3-4-9(7)12-10/h3-6,12H,2H2,1H3

SMILES: CCOC(=O)c1cc2cc(ccc2[nH]1)N(=O)=O

Synonyms:

• 5-Nitroindole-2-Carboxylic Acid Ethyl Ester
• Labotest-Bb Lt00441291
• Ethyl 5-Nitro-1H-Indole-2-Carboxylate
• Ethyl 5-Nitro-2-Carboxylate
• Oxalic Acid Mono-(N-Methyl)-Amide
• Ethyl 5-Nitro Indole-2-Carbonate
• 5-Nitroindole-2-Carboxylic
• ethyl 5-amino-1H-indole-2-carboxylate
• (Methylamino)(Oxo)Acetic Acid

Ethyl 5-Nitroindole-2-carboxylate

CAS: 16732-57-3

Formula: C₁₁H₁₀N₂O₄

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 234.21

Ref: 3B-E1176

1H-Indole-2-carboxylic acid, 5-nitro-, ethyl ester

CAS: 16732-57-3

Formula: C₁₁H₁₀N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 234.2081

Ref: IN-DA001XAX

Ethyl 5-nitroindole-2-carboxylate

CAS: 16732-57-3

Ref: 7W-GK3057

Ethyl 5-nitro-1H-indole-2-carboxylate

CAS: 16732-57-3

Ethyl 5-nitro-1H-indole-2-carboxylate

Formula: C₁₁H₁₀N₂O₄

Purity: 98%

Color and Shape: yellow-brown solid

Molecular weight: 234.21g/mol

Ref: 54-OR2221

Ethyl 5-Nitroindole-2-Carboxylate

CAS: 16732-57-3

Ethyl 5-Nitroindole-2-Carboxylate is a precursor to the anti-HIV drug Delavirdine. It is synthesized by condensation of ethyl pyruvate and urea derivative in the presence of thionyl chloride. This compound can be used as an intermediate in the synthesis of other compounds such as ethyl ester and ethyl pyruvate. The chemical reaction is carried out at room temperature using a chlorinated solvent such as methylene chloride or chloroform. Ethyl 5-nitroindole-2-carboxylate can also be used for the synthesis of other drugs, including antitumor agents.

Formula: C₁₁H₁₀N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 234.21 g/mol

Ref: 3D-FE56789

5-Nitroindole-2-carboxylic acid ethyl ester

CAS: 16732-57-3

5-Nitroindole-2-carboxylic acid ethyl ester is a high quality chemical that has been used as a reagent, intermediate, and building block in the synthesis of various complex compounds. This compound is useful for research and development in the synthesis of useful scaffolds and building blocks. 5-Nitroindole-2-carboxylic acid ethyl ester is a fine chemical with CAS No. 16732-57-3. It is also a versatile building block for the synthesis of many different types of compounds. The compound can be used as a reaction component for the preparation of speciality chemicals, such as research chemicals and pharmaceuticals.

Formula: C₁₁H₁₀N₂O₄

Purity: Min. 98.0 Area-%

Molecular weight: 234.21 g/mol

Ref: 3D-N-3303

Ethyl 5-nitro-1H-indole-2-carboxylate

CAS: 16732-57-3

Formula: C₁₁H₁₀N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 234.211

Ref: 10-F023382