CAS 167479-78-9

L-4-Cyanophenylalanine

Description:

L-4-Cyanophenylalanine is an amino acid derivative characterized by the presence of a cyanophenyl group attached to the phenylalanine backbone. This compound features a cyanide group (-CN) at the para position of the phenyl ring, which can influence its chemical reactivity and biological properties. It is typically used in biochemical research, particularly in studies involving protein synthesis and modification, as it can serve as a building block for peptides or proteins with unique functionalities. The presence of the cyano group may impart specific electronic properties, making it useful in various applications, including drug design and materials science. L-4-Cyanophenylalanine is generally soluble in polar solvents, and its stability can be affected by environmental conditions such as pH and temperature. As with many amino acid derivatives, it is important to handle this compound with care, considering potential toxicity and reactivity. Overall, L-4-Cyanophenylalanine is a valuable compound in the field of organic chemistry and biochemistry, contributing to the understanding of amino acid behavior and protein engineering.

Formula: C₁₀H₁₀N₂O₂

InChI: InChI=1/C10H10N2O2/c11-6-8-3-1-7(2-4-8)5-9(12)10(13)14/h1-4,9H,5,12H2,(H,13,14)/t9-/m0/s1

SMILES: c1cc(ccc1C[C@@H](C(=O)O)N)C#N

Synonyms:

• L-4-Cyanophe
• L-Phe(4-Cn)
• L-(P-Cyano)Phenylalanine
• (L)-Cyanophenylalanine
• H-4-Cyano-Phe-Oh
• H-Phe(P-Cn)-Oh
• H-P-Cyano-L-Phe-Oh
• H-Phe(4-Cn)-Oh
• H-p-Cyano-Phe-OH
• 4-cyano-L-phenylalanine
• (S)-2-amino-3-(4-cyanophenyl)propanoic acid
• L-4-Cyanphenylalanine
• L-4-CN-Phe-OH
• (2S)-2-Amino-3-(4-cyanophenyl)propanoic acid
• L-4-CYANOPHENYLALANINE
• P-CYANO-L-PHENYLALANINE
• (P-CN)PHE-OH
• RARECHEM BK PT 0157
• (2R)-2-amino-3-(4-cyanophenyl)propanoic acid

4-Cyano-L-phenylalanine, 95%

CAS: 167479-78-9

4-Cyano-L-phenylalanine used as a intermediate in organic synthesis, pharmaceutical, chemical research and biochemical application. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy

Formula: C₁₀H₁₀N₂O₂

Purity: 95%

Color and Shape: Solid, White to off-white

Molecular weight: 190.2

Ref: 02-H63572

H-4-Cyano-Phe-OH

CAS: 167479-78-9

Key intermediate for the synthesis of amidines, which can be used as arginine mimetics. McMurray obtained p-Tetrazolylphenylalanine by 1,3-dipolar cycloaddition with trimethyltin azide. Additionally, p-Cyanophenylalanine may serve as well as a IR- or Raman-probe in peptides and recombinant proteins. As a fluorophore, it has been used in combination with Trp in FRET substrates.

Formula: C₁₀H₁₀N₂O₂

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 190.2

Ref: 01-4028063

L-(S)-4-Cyanophenylalanine

CAS: 167479-78-9

Formula: C₁₀H₁₀N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 190.1986

Ref: IN-DA00HZ6X

4-Cyano-L-phenylalanine

CAS: 167479-78-9

4-Cyano-L-phenylalanine

Purity: 98%

Color and Shape: Off-White Solid

Molecular weight: 190.1986g/mol

Ref: 54-OR17450

4-Cyano-L-phenylalanine

CAS: 167479-78-9

4-Cyano-L-phenylalanine is an unnatural aminoacid that has been shown to bind to amyloid protein, which is associated with Alzheimer's disease. The binding of 4-Cyano-L-phenylalanine inhibits the synthesis of amyloid protein and prevents the formation of amyloid fibrils. 4-Cyano-L-phenylalanine also irreversibly inhibits the enzyme responsible for the production of hydrochloric acid in bacteria. The x-ray crystal structures of 4-Cyano L-phenylalanine have been determined and show that this compound binds to the active site of the enzyme synthetase, preventing it from forming an amino acid bond. 4-Cyano L-phenylalanine is an analog of 4-L-phenylalanine and, thanks to its cyano (nitrile) group, is a good candidate for use as a fluorescence marker to study the peptide membrane interactions.

Formula: C₁₀H₁₀N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 190.2 g/mol

Ref: 3D-FC48004

(S)-2-Amino-3-(4-cyanophenyl)propanoic acid

CAS: 167479-78-9

Formula: C₁₀H₁₀N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 190.202

Ref: 10-F224023