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CAS 1675178-56-9

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2′-O-Methyl-5-[[(2-naphthalenylmethyl)amino]carbonyl]uridine

Description:
2′-O-Methyl-5-[[(2-naphthalenylmethyl)amino]carbonyl]uridine is a modified nucleoside that features a uridine base with specific chemical modifications. The presence of a 2′-O-methyl group enhances its stability and can influence its biological activity, particularly in the context of RNA interactions. The 5-position is substituted with a naphthalenylmethyl group linked through an amino and carbonyl moiety, which may impart unique properties such as increased lipophilicity and potential interactions with biological targets. This compound is of interest in medicinal chemistry and biochemistry, particularly for its potential applications in antiviral therapies or as a tool in RNA research. Its structural modifications can affect its binding affinity to RNA and influence its pharmacokinetic properties. As a synthetic nucleoside analog, it may also serve as a substrate for various enzymatic reactions or as a probe in studies of nucleic acid function. Overall, the characteristics of this compound make it a valuable subject for further investigation in the fields of drug development and molecular biology.
Formula:C22H23N3O7
InChI:InChI=1S/C22H23N3O7/c1-31-18-17(27)16(11-26)32-21(18)25-10-15(20(29)24-22(25)30)19(28)23-9-12-6-7-13-4-2-3-5-14(13)8-12/h2-8,10,16-18,21,26-27H,9,11H2,1H3,(H,23,28)(H,24,29,30)/t16-,17-,18-,21-/m1/s1
InChI key:InChIKey=GDRHQLOQYOBSAI-NEYJZJCJSA-N
SMILES:O(C)[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C=C(C(NCC3=CC4=C(C=C3)C=CC=C4)=O)C(=O)NC2=O
Synonyms:
  • 5-(N-2-Naphthylmethylcarboxyamide)-2′-O-methyluridine
  • 2′-O-Methyl-5-[[(2-naphthalenylmethyl)amino]carbonyl]uridine
  • Uridine, 2′-O-methyl-5-[[(2-naphthalenylmethyl)amino]carbonyl]-
  • 5-Naphthyl-β-methylaminocarbony-2’-O-methyluridine
  • 5-Naphthyl-beta-MethylaMinocarbony-2'-O-Methyl-uridine
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