CAS 1675201-90-7

BMS 8

CAS: 1675201-90-7

Formula: C₂₇H₂₈BrNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 494.4201

Ref: IN-DA01EPQ9

BMS-8

CAS: 1675201-90-7

BMS-8

Purity: ≥98%

Molecular weight: 494.42g/mol

Ref: 54-BUP07829

BMS-8

CAS: 1675201-90-7

BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.

Formula: C₂₇H₂₈BrNO₃

Purity: 98.88%

Color and Shape: Solid

Molecular weight: 494.42

Ref: TM-T26859

BMS-8

CAS: 1675201-90-7

BMS-8 is a monoclonal antibody that binds to the death ligand, TNF-α. It has been shown to be effective in treating cancer cells that have an overactive PD-1 pathway, which leads to cell death by inhibiting the production of proteins vital for cell division. BMS-8 has also been shown to inhibit the activity of ctla-4 and pd-l1, molecules that are involved in the TNF-α pathway. The binding of BMS-8 to these molecules has been shown to inhibit their activation and downstream signaling pathways.

Formula: C₂₇H₂₈BrNO₃

Purity: Min. 95%

Molecular weight: 494.4 g/mol

Ref: 3D-ASC20190