CAS 16754-79-3

6-CHLORO-7-DEAZA-9-(2',3',5'-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL)PURINE

Description:

6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-beta-D-ribofuranosyl)purine is a purine derivative characterized by the presence of a chlorine atom at the 6-position and a deaza substitution at the 7-position of the purine ring. The compound features a ribofuranosyl moiety that is fully acetylated at the 2', 3', and 5' hydroxyl groups, which enhances its stability and lipophilicity. This structural modification can influence its biological activity, making it a potential candidate for nucleoside analogs in medicinal chemistry. The presence of the deaza substitution alters the electronic properties of the purine base, potentially affecting its interaction with nucleic acid targets. The compound is of interest in research related to antiviral and anticancer therapies, as modifications to nucleosides can lead to improved efficacy and reduced toxicity. Its CAS number, 16754-79-3, allows for easy identification in chemical databases and literature. Overall, this compound exemplifies the intricate design of nucleoside analogs for therapeutic applications.

Formula: C₁₇H₁₈ClN₃O₇

InChI: InChI=1/C17H18ClN3O7/c1-8(22)25-6-12-13(26-9(2)23)14(27-10(3)24)17(28-12)21-5-4-11-15(18)19-7-20-16(11)21/h4-5,7,12-14,17H,6H2,1-3H3/t12-,13+,14+,17-/m1/s1

Synonyms:

• 6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl diacetate

CAS: 16754-79-3

Formula: C₁₇H₁₈ClN₃O₇

Purity: 97%

Color and Shape: Liquid

Molecular weight: 411.7937

Ref: IN-DA001XGE

6-Chloro-7-deaza-9-(2'',3'',5''-tri-O-acetyl-b-D-ribofuranosyl)purine

CAS: 16754-79-3

Ref: 7W-GN0631

6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

CAS: 16754-79-3

Nucleoside Derivatives - 7-Deazapurine nucleosides; Halo-nucleosides; Scaffolds and Templates

Formula: C₁₇H₁₈ClN₃O₇

Color and Shape: Solid

Molecular weight: 411.79

Ref: TM-TNU1301

6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine

CAS: 16754-79-3

6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a monophosphate nucleoside analog that is used as an antiviral agent. It is a synthetic compound that is activated by phosphorylation to form the triphosphate, which inhibits viral DNA synthesis by binding to the RNA polymerase enzyme. 6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine has been shown to be effective against cancer cells in vitro and in vivo and may be useful for the treatment of human immunodeficiency virus (HIV).

Formula: C₁₇H₁₈ClN₃O₇

Purity: Min. 97 Area-%

Color and Shape: Clear Liquid

Molecular weight: 411.79 g/mol

Ref: 3D-NC06328

6-Chloro-7-deaza-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranoysyl)purine

Controlled Product

CAS: 16754-79-3

Formula: C₁₇H₁₈ClN₃O₇

Color and Shape: Neat

Molecular weight: 411.794

Ref: TR-C365187