CAS 1676-81-9

N-[(Phenylmethoxy)carbonyl]-L-serine methyl ester

Description:

N-[(Phenylmethoxy)carbonyl]-L-serine methyl ester, with the CAS number 1676-81-9, is an organic compound characterized by its structure, which includes a serine amino acid derivative. This compound features a phenylmethoxycarbonyl (PMOC) protecting group, which enhances its stability and solubility in organic solvents. The presence of the methyl ester group contributes to its reactivity, making it useful in various chemical reactions, particularly in peptide synthesis and as an intermediate in organic synthesis. The compound is typically a white to off-white solid, and its solubility is influenced by the polar nature of the serine moiety and the non-polar characteristics of the phenyl group. It is important in biochemical applications, especially in the study of enzyme mechanisms and the development of pharmaceuticals. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken. Overall, this compound serves as a valuable tool in both synthetic and medicinal chemistry.

Formula: C₁₂H₁₅NO₅

InChI: InChI=1S/C12H15NO5/c1-17-11(15)10(7-14)13-12(16)18-8-9-5-3-2-4-6-9/h2-6,10,14H,7-8H2,1H3,(H,13,16)/t10-/m0/s1

InChI key: InChIKey=CINAUOAOVQPWIB-JTQLQIEISA-N

SMILES: C(OC(N[C@H](C(OC)=O)CO)=O)C1=CC=CC=C1

Synonyms:

• (2S)-2-[(Benzyloxycarbonyl)amino]-3-hydroxypropionic acid methyl ester
• (Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-serine methyl ester
• <span class="text-smallcaps">L</span>-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester
• Methyl (2S)-2-[(benzyloxycarbonyl)amino]-3-hydroxypropanoate
• Methyl (S)-2-((benzyloxycarbonyl)amino)-3-hydroxypropanoate
• Methyl N-(benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-serinate
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-serine methyl ester
• N-(Benzyloxycarbonyl)serine methyl ester
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-serine methyl ester
• N-Carbobenzoxy-L-serine methyl ester
• N-Cbz-<span class="text-smallcaps">L</span>-serine methyl ester
• N-Cbz-L-Serine Methyl Ester
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-serine methyl ester
• Serine, N-carboxy-, N-benzyl methyl ester
• Serine, N-carboxy-, N-benzyl methyl ester, <span class="text-smallcaps">L</span>-
• Z-Ser-OMe
• methyl N-[(benzyloxy)carbonyl]-L-serinate
• N-[(Phenylmethoxy)carbonyl]-L-serine methyl ester
• (Benzyloxycarbonyl)-L-serine methyl ester
• L-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester

N-Benzyloxycarbonyl-L-serine Methyl Ester

CAS: 1676-81-9

Formula: C₁₂H₁₅NO₅

Purity: >98.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 253.25

Ref: 3B-C1403

Z-Ser-OMe

CAS: 1676-81-9

Formula: C₁₂H₁₅NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 253.2512

Ref: IN-DA00HZ77

N-Z-L-serine methyl ester

CAS: 1676-81-9

Molecular weight: 253.25

Ref: 7W-GM6048

Z-Ser-Ome

CAS: 1676-81-9

Z-Ser-Ome

Purity: 98%

Molecular weight: 253.25g/mol

Ref: 54-OR1015464

Z-Ser-Ome

CAS: 1676-81-9

M06266 - Z-Ser-Ome

Formula: C₁₂H₁₅NO₅

Purity: 95%

Color and Shape: Liquid

Molecular weight: 253.254

Ref: 10-M06266

N-[(Phenylmethoxy)carbonyl]-L-serine Methyl Ester

Controlled Product

CAS: 1676-81-9

Applications N-[(Phenylmethoxy)carbonyl]-L-serine Methyl Ester is used to inhibit the activity of Mycobacterium tuberculosis in studies. Also used in the synthesis of pyrazinecarboxamide-based compounds acting as inhibitors of diacylglycerol acetyltransferases regarding treatment of obesity.
References Barlind,J.G. et al.: J. Med. Chem., 55, 10610 (2012); Pinheiro, A.C. et al.: J. Res. Chem., 3, 180 (2007);

Formula: C₁₂H₁₅NO₅

Color and Shape: Neat

Molecular weight: 253.25

Ref: TR-P335725