CAS 167698-69-3

Z-Arg-Leu-Arg-Gly-Gly-AMC

CAS: 167698-69-3

Z-RLRGG-AMC is a fluorogenic substrate for the deubiquitinating enzyme isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases (UCHs) based on the C-termini of ubiquitin with a kcat/Km value of 95 M⁻¹s⁻¹. Together with our product I-1685 it is used in continuous assays for precise mechanistic studies or microtiter plate assays for high-throughput inhibitor screening.

Formula: C₄₀H₅₆N₁₂O₉

Purity: 98.5%

Color and Shape: White

Molecular weight: 848.96

Ref: 01-4027158

Z-Arg-Leu-Arg-Gly-Gly-AMC acetate

CAS: 167698-69-3

Z-Arg-Leu-Arg-Gly-Gly-AMC acetate is a protease inhibitor that blocks the activity of the proteasome. It has been shown to inhibit the activity of histidine proteases and to inhibit proteolysis by the proteasome in a kinetic assay. This inhibitor also inhibits coronavirus replication, which may be due to its ability to bind to histidine residues on proteins involved in viral replication. Z-Arg-Leu-Arg-Gly-Gly-AMC acetate is expressed in transfected cells as an enzyme with a polymerase chain reaction (PCR) product and has been shown to prevent viral replication.

Formula: C₄₀H₅₆N₁₂O₉•(C₂H₄O₂)x

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 848.95 g/mol

Ref: 3D-FA110572