CAS 1677667-24-1

4-[3-[2-Chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-2-hydroxybenzoic acid

CAS: 1677667-24-1

4-[3-[2-Chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-2-hydroxybenzoic acid is a potent inhibitor of antibody production and is used as a research tool for cell biology, peptides, pharmacology, and ion channels. This compound binds to the ATP binding site of the enzyme protein kinase A (PKA), inhibiting both cAMP-dependent and independent pathways. 4-[3-[2-Chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-2-hydroxybenzoic acid also blocks ion channel function by binding to the voltage sensor domain of potassium channels. It has been shown to inhibit receptor function in vitro.

Formula: C₂₂H₁₂ClF₃N₂O₄

Purity: Min. 95%

Molecular weight: 460.8 g/mol

Ref: 3D-CSC66724

GNE-0946

CAS: 1677667-24-1

GNE-0946 is an effective and selective RORγ/RORc/NR1F3 antagonist (inverse agonist) with an EC50 of 4 nM in HEK-293 cells. autoimmune disease research.

Formula: C₂₂H₁₂ClF₃N₂O₄

Color and Shape: Solid

Molecular weight: 460.79

Ref: TM-T15398