TASIN-1 hydrochloride, identified by its CAS number 1678515-13-3, is a chemical compound that has garnered attention in pharmaceutical research, particularly for its potential therapeutic applications. It is characterized as a small molecule with a specific molecular structure that contributes to its biological activity. The hydrochloride salt form enhances its solubility in aqueous solutions, which is crucial for drug formulation and bioavailability. TASIN-1 is known to interact with specific biological targets, making it a subject of interest in studies related to various diseases. Its pharmacological profile may include properties such as anti-inflammatory or anti-cancer effects, although detailed mechanisms of action and efficacy are typically explored in preclinical and clinical studies. As with many compounds in drug development, safety, toxicity, and pharmacokinetics are critical factors that are evaluated to determine its suitability for therapeutic use. Overall, TASIN-1 hydrochloride represents a promising candidate in the ongoing search for effective treatments in modern medicine.

TASIN-1 (1678515-13-3) selectively induces apoptosis in cells with truncations in the adenomatous polyposis coli (APC) gene (but not normal cells or wild type cancer cells), an important multifunctional tumor suppressor gene.1 IC50 = 70nM for DLD1 cell line.? It inhibited cancer cell growth in human tumor xenografts (DLD1 and HT29 tumors) and a genetically engineered mouse model (CPC;Apc) of colorectal cancer.? TASIN-1 induces ER stress-dependent JNK activation with ROS production and AKT inhibition via cholesterol depletion.2

TASIN-1 hydrochloride

1678515-13-3: TASIN-1 hydrochloride, identified by its CAS number 1678515-13-3, is a chemical compound that has garnered attention in pharmaceutical research, particularly for its potential therapeutic applications. It is characterized as a small molecule with a specific molecular structure that contributes to its biological activity. The hydrochloride salt form enhances its solubility in aqueous solutions, which is crucial for drug formulation and bioavailability. TASIN-1 is known to interact with specific biological targets, making it a subject of interest in studies related to various diseases. Its pharmacological profile may include properties such as anti-inflammatory or anti-cancer effects, although detailed mechanisms of action and efficacy are typically explored in preclinical and clinical studies. As with many compounds in drug development, safety, toxicity, and pharmacokinetics are critical factors that are evaluated to determine its suitability for therapeutic use. Overall, TASIN-1 hydrochloride represents a promising candidate in the ongoing search for effective treatments in modern medicine.

TASIN-1 Hydrochloride

<p>TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated</p>

CAS 1678515-13-3

TASIN-1 hydrochloride

TASIN-1 Hydrochloride

Ref: 54-BUP15201

TASIN-1 Hydrochloride

Ref: TM-T24855