CAS 167882-66-8

(-)-Wilforol A

Description:

(-)-Wilforol A is a naturally occurring compound classified as a terpenoid, specifically a type of sesquiterpene. It is derived from the plant Wilfordia ebracteata, which is known for its traditional medicinal uses. This compound exhibits a complex molecular structure characterized by multiple chiral centers, contributing to its stereochemistry and biological activity. (-)-Wilforol A has garnered interest in pharmacological research due to its potential anti-inflammatory and anticancer properties. Its mechanism of action may involve modulation of various signaling pathways, although detailed studies are still ongoing to elucidate its full biological effects. The compound is typically studied in the context of natural product chemistry and may serve as a lead compound for the development of new therapeutic agents. As with many natural products, its extraction and purification can be challenging, necessitating advanced techniques in organic chemistry. Overall, (-)-Wilforol A represents a significant area of interest for researchers exploring the intersection of natural compounds and medicinal chemistry.

Formula: C₂₉H₃₈O₅

InChI: InChI=1S/C29H38O5/c1-16-22-17(13-19(31)23(16)32)27(4)10-12-29(6)21-15-26(3,24(33)34)8-7-25(21,2)9-11-28(29,5)20(27)14-18(22)30/h13-14,21,31-32H,7-12,15H2,1-6H3,(H,33,34)/t21-,25-,26-,27+,28-,29+/m1/s1

InChI key: InChIKey=MIQDJLKXHZPMHH-CPISFEQASA-N

SMILES: C[C@@]12[C@](C)([C@]3([C@@](C)(CC1)CC[C@](C(O)=O)(C)C3)[H])CC[C@]4(C)C2=CC(=O)C=5C4=CC(O)=C(O)C5C

Synonyms:

• D:A-Friedo-24-noroleana-1,3,5(10),7-tetraen-29-oic acid, 2,3-dihydroxy-6-oxo-, (20α)-
• 24,25,26-Trinoroleana-1,3,5(10),7-tetraen-29-oic acid, 2,3-dihydroxy-9,13-dimethyl-6-oxo-, (9β,13α,14β,20α)-
• (-)-Wilforol A
• (9β,13α,14β,20α)-2,3-Dihydroxy-9,13-dimethyl-6-oxo-24,25,26-trinoroleana-1,3,5(10),7-tetraen-29-oic acid
• Wilforol A

Wilforol A

CAS: 167882-66-8

Wilforol A is a natural product from Tripterygium wilfordii Hook. f.

Formula: C₂₉H₃₈O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 466.61

Ref: TM-TN5255

Wilforol A

CAS: 167882-66-8

Wilforol A is a diterpenoid lactone, which is a natural compound extracted from the plant Tripterygium wilfordii. This compound originates from traditional Chinese medicine, where it has been used for centuries for its therapeutic properties. The mode of action of Wilforol A involves the inhibition of pro-inflammatory cytokines and modulation of immune responses, which contributes to its potent anti-inflammatory effects.

Formula: C₂₉H₃₈O₅

Purity: Min. 95%

Molecular weight: 466.60 g/mol

Ref: 3D-SGA88266