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CAS 16789-98-3

:

Desmopressin Acetate

Description:
Desmopressin acetate is a synthetic analog of vasopressin, a naturally occurring hormone that regulates water retention in the body. It is primarily used in the treatment of conditions such as diabetes insipidus and bedwetting (nocturnal enuresis). This compound is characterized by its ability to enhance water reabsorption in the kidneys, thereby reducing urine output. Desmopressin acetate is typically administered in a nasal spray or oral tablet form, and it exhibits a longer duration of action compared to vasopressin due to its modified structure, which increases its resistance to enzymatic degradation. The substance is soluble in water and has a relatively low molecular weight. Its pharmacological effects are primarily mediated through the V2 receptors in the renal collecting ducts. While generally well-tolerated, potential side effects may include headache, nausea, and changes in blood sodium levels. As with any medication, it is important to use desmopressin acetate under medical supervision to monitor for efficacy and safety.
Formula:C46H64N14O12S2・2(C2H4O<
InChI:InChI=1/C46H64N14O12S2.2C2H4O2/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)24-74-73-19-16-38(65)54-30(21-26-10-12-27(61)13-11-26)41(68)57-31(42(69)55-29)20-25-6-2-1-3-7-25;2*1-2(3)4/h1-3,6-7,10-13,28-34,61H,4-5,8-9,14-24H2,(H2,47,62)(H2,48,63)(H2,49,64)(H,53,66)(H,54,65)(H,55,69)(H,56,71)(H,57,68)(H,58,67)(H,59,70)(H4,50,51,52);2*1H3,(H,3,4)
SMILES:c1ccc(cc1)CC1C(=NC(CCC(=N)O)C(=NC(CC(=N)O)C(=NC(CSSCCC(=NC(Cc2ccc(cc2)O)C(=N1)O)O)C(=O)N1CCCC1C(=NC(CCCNC(=N)N)C(=NCC(=N)O)O)O)O)O)O.CC(=O)O.CC(=O)O
Synonyms:
  • 1-(3-Mercaptopropionic Acid)-8-D-Arginine-Vasopressin Diacetate
  • 1-Deamino-8-D-Arginine-Vasopressin Diacetate
  • DesmopressinAcetate
  • Ddavp
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