CAS 1679-18-1

(4-Chlorophenyl)boronic acid

Description:

(4-Chlorophenyl)boronic acid, with the CAS number 1679-18-1, is an organoboron compound characterized by the presence of a boronic acid functional group attached to a chlorinated phenyl ring. This compound typically appears as a white to off-white solid and is soluble in polar organic solvents such as methanol and ethanol. Its structure features a boron atom bonded to a hydroxyl group and a phenyl ring that has a chlorine substituent at the para position. (4-Chlorophenyl)boronic acid is known for its utility in organic synthesis, particularly in cross-coupling reactions, such as Suzuki-Miyaura coupling, which allows for the formation of carbon-carbon bonds. Additionally, it can serve as a ligand in coordination chemistry and has applications in the development of sensors and pharmaceuticals. The compound is also notable for its ability to form reversible complexes with diols, making it useful in various biochemical applications. Safety precautions should be taken when handling this substance, as it may pose health risks if ingested or inhaled.

Formula: C₆H₆BClO₂

InChI: InChI=1S/C6H6BClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H

InChI key: InChIKey=CAYQIZIAYYNFCS-UHFFFAOYSA-N

SMILES: B(O)(O)C1=CC=C(Cl)C=C1

Synonyms:

• (4-Chlorophenyl)boronic acid
• (P-Chlorophenyl)Metaboric Acid
• (p-Chlorophenyl)boronic acid
• (p-Chlorphenyl)metaborsaure
• 4-Chlorobenzeneboronic Acid
• 4-Chlorophenylbornic Acid
• 4-Chlorophenylboroic Acid
• Acide (P-Chlorophenyl)Metaborique
• Acido (P-Clorofenil)Metaborico
• Akos Brn-0011
• B-(4-Chlorophenyl)boronic acid
• Benzeneboronic acid, p-chloro-
• Boronic Acid, (4-Chlorophenyl)-
• Boronic acid, B-(4-chlorophenyl)-
• Nsc 25408
• P-Chloro Benzene Boronic Acid
• P-Chlorophenylboronic Acid
• Rarechem Ah Pb 0178

4-Chlorobenzeneboronic acid, 98+%

CAS: 1679-18-1

Used as a GC reagent for diols. It is a reagent used for palladium-catalyzed direct arylation, cyclopalladation, tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation, copper-mediated ligandless aerobic fluoroalkylation, Pd-catalyzed arylative cyclization, ruthenium c

Formula: C₆H₆BClO₂

Purity: 98+%

Color and Shape: White to pale cream to pale brown, Powder or crystalline powder

Molecular weight: 156.37

Ref: 02-A15657

(4-Chlorophenyl)boronic acid

CAS: 1679-18-1

Formula: C₆H₆BClO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 156.3746

Ref: IN-DA00340A

4-Chlorophenylboronic acid

CAS: 1679-18-1

Formula: C₆H₆BClO₂

Molecular weight: 156.38

Ref: 7W-GK7779

4-Chlorophenylboronic Acid (contains varying amounts of Anhydride)

CAS: 1679-18-1

Formula: C₆H₆BClO₂

Purity: 97.0 to 114.0 %

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 156.37

Ref: 3B-C1473

4-Chlorophenylboronic acid

CAS: 1679-18-1

Purity: 97%

Molecular weight: 156.37

Ref: FT-C6100

4-Chlorophenylboronic acid

CAS: 1679-18-1

4-Chlorophenylboronic acid

Formula: C₆H₆BClO₂

Purity: 98%

Color and Shape: white to off-white powder

Molecular weight: 156.37g/mol

Ref: 54-OR6643

Vismodegib Impurity 11

CAS: 1679-18-1

Formula: C₆H₆BClO₂

Molecular weight: 156.4

Ref: ST-EA-CP-V25034

4-Chlorobenzeneboronic acid

CAS: 1679-18-1

Formula: C₆H₆BClO₂

Purity: 95%

Color and Shape: Solid, Powder to crystalline powder

Molecular weight: 156.37

Ref: 10-F010986

4-Chlorophenylboronic Acid extrapure, 97%

CAS: 1679-18-1

Formula: C₆H₆BClO₂

Purity: min. 97%

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 156.4

Ref: SR-38825

4-Chlorobenzeneboronic Acid

Controlled Product

CAS: 1679-18-1

Applications 4-Chlorobenzeneboronic Acid is used as a catalyst for the preparation of 4-hydroxycoumarin derivatives which display antitrypanosomal and antioxidant properties. It is also used as a catalyst for the asymmetric borane reduction of electron-deficient ketones.
References Perez-Cruz, F. et al.: Bioorg Med. Chem. Lett., 22, 5569 (2012); Liu, H. et al.: J. Mol. Cata. A. Chem., 244, 68 (2006);

Formula: C₆H₆BClO₂

Color and Shape: Neat

Molecular weight: 156.37

Ref: TR-C364565

4-Chlorophenylboronic acid

CAS: 1679-18-1

4-Chlorophenylboronic acid is a chemical compound that is used in the industrial preparation of biphenyl. It is produced by the Friedel-Crafts reaction between chlorine and 4-methoxyphenylboronic acid. This reaction can be carried out using a variety of solvents, such as chloroform or carbon tetrachloride. The optimal reaction conditions are acidic pH values, which are achieved by adding sodium carbonate to the solution. The product can be purified by distillation or crystallization. 4-Chlorophenylboronic acid can also be used for the synthesis of organic compounds through cross-coupling reactions with organometallic reagents, such as palladium chloride and triphenylphosphine, or through asymmetric synthesis with chiral ligands like (S)-proline and 2-(diphenylphosphino)ferrocene.

Formula: C₆H₆BClO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 156.37 g/mol

Ref: 3D-FC08281