CAS 167933-07-5

Flibanserin

Description:

Flibanserin is a pharmaceutical compound primarily used in the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. It functions as a serotonin receptor agonist and antagonist, specifically targeting the 5-HT1A and 5-HT2A receptors, which play a role in sexual desire and arousal. The substance is typically administered orally and is known for its unique mechanism of action, which differs from traditional treatments for sexual dysfunction. Flibanserin is characterized by its relatively low bioavailability and a half-life that necessitates once-daily dosing, usually at bedtime, to minimize side effects such as dizziness and nausea. It is important to note that Flibanserin is not an aphrodisiac and does not enhance sexual performance; rather, it aims to restore sexual desire. Additionally, the use of Flibanserin is contraindicated in patients who consume alcohol due to the risk of severe hypotension and syncope. Overall, Flibanserin represents a novel approach to addressing sexual desire issues in women, with a focus on neurochemical pathways.

Formula: C₂₀H₂₁F₃N₄O

InChI: InChI=1S/C20H21F3N4O/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28/h1-7,14H,8-13H2,(H,24,28)

InChI key: InChIKey=PPRRDFIXUUSXRA-UHFFFAOYSA-N

SMILES: C(CN1CCN(CC1)C2=CC(C(F)(F)F)=CC=C2)N3C=4C(NC3=O)=CC=CC4

Synonyms:

• 1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one
• 1-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1,3-dihydro-2H-benzimidazol-2-one
• 1-(2-{4-[4-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-1,3-dihydro-2H-benzimidazol-2-one
• 2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-
• 3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one
• Addyi
• Bimt 17
• Bimt 17Bs
• Flibanserin

2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-

CAS: 167933-07-5

Formula: C₂₀H₂₁F₃N₄O

Purity: 99%

Color and Shape: Solid

Molecular weight: 390.4021

Ref: IN-DA001XOQ

Flibanserin

CAS: 167933-07-5

Flibanserin

Purity: ≥98%

Molecular weight: 390.4g/mol

Ref: 54-BUP13157

Flibanserin

CAS: 167933-07-5

Flibanserin

Purity: 99%

Molecular weight: 390.4g/mol

Ref: 54-PC109222

Flibanserin

CAS: 167933-07-5

Formula: C₂₀H₂₁F₃N₄O

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 390.41

Ref: 3B-F1239

Flibanserin

CAS: 167933-07-5

Formula: C₂₀H₂₁F₃N₄O

Color and Shape: Neat

Molecular weight: 390.40

Ref: 86-MM3222.00

Flibanserin

CAS: 167933-07-5

Ref: 7W-GW2705

Flibanserin

CAS: 167933-07-5

Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder.

Formula: C₂₀H₂₁F₃N₄O

Purity: 99.37% - 99.93%

Color and Shape: White Powder

Molecular weight: 390.4

Ref: TM-T4297

Flibanserin

Controlled Product

CAS: 167933-07-5

Formula: C₂₀H₂₁F₃N₄O

Color and Shape: Neat

Molecular weight: 390.40

Ref: TR-F336750

Flibanserin

CAS: 167933-07-5

Flibanserin is a drug that is used to treat hypoactive sexual desire disorder in women. This drug has been found to increase serotonin levels in the brain by binding to 5-HT2 receptors. Flibanserin has been shown to have significant effects on body mass index, locomotor activity, and estradiol benzoate levels. Its pharmacological mechanism of action is not fully understood, but it may be due to matrix effects or changes in the hypothalamic-pituitary-adrenal axis. Flibanserin has an effect on the physiological effects such as sleep and mood, with its use being accompanied by an improvement in depression scores. Flibanserin is metabolized through different pathways including CYP3A4 and CYP2D6 enzymes, which are also responsible for its pharmacokinetic properties.

Formula: C₂₀H₂₁F₃N₄O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 390.4 g/mol

Ref: 3D-FT76243