CAS 1679333-73-3

1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-(2,4-dichlorophenyl)-2,3,4,9-tetrahydro-, (1R,3S)-

Description:

1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-(2,4-dichlorophenyl)-2,3,4,9-tetrahydro-, (1R,3S)- is a complex organic compound characterized by its bicyclic structure, which includes a pyridoindole framework. This compound features a carboxylic acid functional group, contributing to its acidity and potential reactivity. The presence of a dichlorophenyl substituent indicates that it may exhibit unique electronic properties and biological activity, often associated with halogenated aromatic compounds. The stereochemistry, denoted by (1R,3S), suggests specific spatial arrangements of atoms, which can influence the compound's interactions in biological systems. This compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural features that could interact with biological targets. Additionally, its molecular weight, solubility, and stability under various conditions would be important characteristics to consider for practical applications. Overall, this compound exemplifies the complexity and diversity found in organic chemistry, particularly in the context of drug design and development.

Formula: C₁₈H₁₄Cl₂N₂O₂

Synonyms:

• MMV008138
• 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-(2,4-dichlorophenyl)-2,3,4,9-tetrahydro-, (1R,3S)-

ML218

CAS: 1679333-73-3

ML218

Purity: ≥98%

Molecular weight: 369.33g/mol

Ref: 54-BUP20839

MMV008138

CAS: 1679333-73-3

MMV008138 is an antimalarial compound, which is a synthetic chemical entity derived from medicinal chemistry efforts aimed at targeting malaria. The source of MMV008138 is the pharmaceutical research pipeline focused on identifying new antimalarial agents. It operates by inhibiting the Plasmodium falciparum enzyme PfNDH2, an essential component in the parasite’s respiratory chain, disrupting its energy production capabilities and ultimately leading to parasite death.

Formula: C₁₈H₁₄Cl₂N₂O₂

Purity: Min. 95%

Molecular weight: 361.2 g/mol

Ref: 3D-ESC33373

MMV008138

CAS: 1679333-73-3

MMV008138 inhibits the growth of P. falciparum Dd2 strain (IC50 of 250 nM).

Formula: C₁₈H₁₄Cl₂N₂O₂

Color and Shape: Solid

Molecular weight: 361.22

Ref: TM-T12084