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CAS 16801-62-0

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N-CBZ-4-HYDROXYCYCLOHEXANE

Description:
N-CBZ-4-hydroxycyclohexane, also known as N-carbobenzyloxy-4-hydroxycyclohexanamine, is an organic compound characterized by the presence of a carbobenzyloxy (CBZ) protecting group attached to a 4-hydroxycyclohexane moiety. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and methanol, but has limited solubility in water. The CBZ group serves as a protective group for amines, making this compound useful in organic synthesis, particularly in the preparation of pharmaceuticals and other complex organic molecules. The presence of the hydroxy group contributes to its reactivity, allowing for further functionalization. Additionally, the cyclohexane ring provides a degree of rigidity and steric hindrance, influencing the compound's chemical behavior and interactions. As with many organic compounds, handling should be done with care, following appropriate safety protocols to mitigate any potential hazards associated with its use.
Formula:C14H19NO3
InChI:InChI=1/C14H19NO3/c16-13-8-6-12(7-9-13)15-14(17)18-10-11-4-2-1-3-5-11/h1-5,12-13,16H,6-10H2,(H,15,17)
SMILES:c1ccc(cc1)COC(=NC1CCC(CC1)O)O
Synonyms:
  • 4-(Z-Amino)Cyclohexanol
  • Carbamic acid, (4-hydroxycyclohexyl)-, phenylmethyl ester
  • N-Cbz-4-Amino-Cyclohexanol
  • ((4-Hydroxycyclohexyl)carbamic acid benzyl ester), (Cbz-amino)-4-hydroxycyclohexane
  • Benzyl (4-Hydroxycyclohexyl)Carbamate
  • trans-1-Cbz-amino-4-hydroxycyclohexane
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