CAS 16808-86-9

6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride (1:1), (5α,7α)-

Description:

6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride (1:1), (5α,7α)-, identified by CAS number 16808-86-9, is a synthetic compound belonging to the morphinan class of alkaloids. This substance exhibits a complex molecular structure characterized by multiple functional groups, including methanol, epoxy, and hydroxy groups, which contribute to its pharmacological properties. It is typically encountered in the context of research related to analgesics and potential therapeutic agents due to its interaction with opioid receptors. The presence of the cyclopropylmethyl group may influence its binding affinity and selectivity, impacting its efficacy and safety profile. As a hydrochloride salt, it is likely to be more soluble in water, facilitating its use in various formulations. Safety and handling precautions are essential, as with many compounds in this class, due to potential psychoactive effects and regulatory considerations.

Formula: C₂₆H₃₅NO₄·ClH

InChI: InChI=1S/C26H35NO4.ClH/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25;/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3;1H/t18-,19-,22-,24-,25+,26-;/m1./s1

InChI key: InChIKey=UNPUINKKJUSSDZ-UVGWPQHUSA-N

SMILES: O(C)[C@@]12[C@]3([C@]45[C@@]([C@](N(CC6CC6)CC4)(CC7=C5C(O3)=C(O)C=C7)[H])(C[C@@H]1[C@@](C)(C)O)CC2)[H].Cl

Synonyms:

• (5alpha,7alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-6,14-ethenomorphinan-7-methanol hydrochloride
• 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride (1:1), (5α,7α)-
• 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, hydrochloride, (5α,7α)-
• 6,14-Ethenomorphinan-7-methanol, 18,19-dihydro-17-(cyclopropylmethyl)-alpha,alpha-dimethyl-4,5-epoxy-3-hydroxy-6-methoxy-, hydrochloride, (5-alpha,7-alpha)-
• 6,14-endo-Ethanetetrahydrooripavine, 21-cyclopropyl-7-alpha-(1-hydroxy-1-methylethyl)-, HCl
• 6,14-endo-Ethanotetrahydrooripavine, 21-cyclopropyl-7α-(1-hydroxy-1-methylethyl)-, hydrochloride
• Diprenorphine hydrochloride
• Revivon

Diprenorphine Hydrochloride (1 mg/ml in Methanol)

Controlled Product

CAS: 16808-86-9

Formula: C₂₆H₃₅NO₄·ClH

Color and Shape: Single Solution

Molecular weight: 462.02

Ref: TR-KIT4458

Diprenorphine-d3 Hydrochloride

Controlled Product

CAS: 16808-86-9

Applications Labelled Diprenorphine (D492100). Diprenorphine is a narcotic antagonist. Diprenorphine is closely related to Cyprenorphine.
References Blane, G.F., et al.: J. Pharm. Pharmacol., 19, 367 (1967), Grange, M., et al.: Rev. Med. Vet., 124, 899 (1973), Pert, C.B., et al.: Life Sci., 16, 1849 (1975), Duggett, N.S., et al.: Toxicol. Appl. Pharmacol., 31, 141 (1977),

Formula: C₂₆H₃₃D₃ClNO₄

Color and Shape: Neat

Molecular weight: 465.04

Ref: TR-D492102

Diprenorphine Hydrochloride

Controlled Product

CAS: 16808-86-9

Applications Diprenorphine is a narcotic antagonist. Diprenorphine is closely related to Cyprenorphine.
References Blane, G.F., et al.: J. Pharm. Pharmacol., 19, 367 (1967), Grange, M., et al.: Rev. Med. Vet., 124, 899 (1973), Pert, C.B., et al.: Life Sci., 16, 1849 (1975), Duggett, N.S., et al.: Toxicol. Appl. Pharmacol., 31, 141 (1977),

Formula: C₂₆H₃₅NO₄·ClH

Color and Shape: Neat

Molecular weight: 462.02

Ref: TR-D492100

Diprenorphine hydrochloride

Controlled Product

CAS: 16808-86-9

Diprenorphine hydrochloride is a drug that belongs to the class of opioids. It is used as an antidote for opioid overdose and has been shown to be effective in reducing the severity of withdrawal symptoms. Diprenorphine hydrochloride has been shown to inhibit P-glycoprotein (P-gp), which is a membrane protein that transports certain substances from the brain back into the blood. This inhibition leads to increased concentrations of dopamine in the brain, which may contribute to its clinical relevance as an anti-psychotic agent. Diprenorphine hydrochloride also has binding affinity for μ-, κ-, δ-, and ν-opioid receptors, which can lead to decreased locomotor activity, antinociceptive effects, and sedation.

Formula: C₂₆H₃₆ClNO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 462.02 g/mol

Ref: 3D-FD22520