CAS 1681056-61-0

(αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide

Description:

The chemical substance with the name "(αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide" and CAS number "1681056-61-0" is characterized by its complex molecular structure, which includes multiple functional groups such as sulfonamides, amides, and heterocycles. This compound features a quinoline moiety, which is known for its biological activity, particularly in medicinal chemistry. The presence of furan and thiophene rings suggests potential interactions with biological targets, making it of interest in drug development. The methoxy group may enhance lipophilicity, influencing the compound's pharmacokinetics. Additionally, the stereochemistry indicated by "(αR)" suggests that the compound has specific spatial arrangements that could affect its biological activity and interactions. Overall, this substance is likely to exhibit unique chemical properties and potential therapeutic applications, warranting further investigation in the context of pharmacology and medicinal chemistry.

Formula: C₂₈H₂₅N₃O₆S₂

InChI: InChI=1S/C28H25N3O6S2/c1-36-25-9-3-2-8-23(25)27(28(33)31(17-20-6-4-14-37-20)18-21-7-5-15-38-21)30-39(34,35)22-11-12-24-19(16-22)10-13-26(32)29-24/h2-16,27,30H,17-18H2,1H3,(H,29,32)/t27-/m1/s1

InChI key: InChIKey=IYIGLWQQAMROOF-HHHXNRCGSA-N

SMILES: [C@@H](C(N(CC1=CC=CO1)CC2=CC=CS2)=O)(NS(=O)(=O)C=3C=C4C(=CC3)NC(=O)C=C4)C5=C(OC)C=CC=C5

Synonyms:

• OSMI 1
• (αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide
• Benzeneacetamide, α-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-, (αR)-

OSMI-1

CAS: 1681056-61-0

Formula: C₂₈H₂₅N₃O₆S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 563.6446

Ref: IN-DA01ENF1

(R)-N-(Furan-2-Ylmethyl)-2-(2-Methoxyphenyl)-2-(2-Oxo-1,2-Dihydroquinoline-6-Sulfonamido)-N-(Thiophen-2-Ylmethyl)Acetamide

CAS: 1681056-61-0

(R)-N-(Furan-2-Ylmethyl)-2-(2-Methoxyphenyl)-2-(2-Oxo-1,2-Dihydroquinoline-6-Sulfonamido)-N-(Thiophen-2-Ylmethyl)Acetamide

Purity: 98%

Molecular weight: 563.64g/mol

Ref: 54-OR1023849

OSMI-1

CAS: 1681056-61-0

OSMI-1

Purity: ≥95%

Molecular weight: 563.64g/mol

Ref: 54-BUP12905

OSMI 1

Controlled Product

CAS: 1681056-61-0

Formula: C₂₈H₂₅N₃O₆S₂

Color and Shape: Neat

Molecular weight: 563.64

Ref: TR-O703585

OSMI 1

CAS: 1681056-61-0

Inhibitor of O-GlcNAc transferase

Formula: C₂₈H₂₅N₃O₆S₂

Purity: Min. 95%

Molecular weight: 563.65 g/mol

Ref: 3D-BO168473

OSMI-1

CAS: 1681056-61-0

OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.

Formula: C₂₈H₂₅N₃O₆S₂

Purity: 96.79% - 99.39%

Color and Shape: Solid

Molecular weight: 563.64

Ref: TM-T16409