CAS 1681056-61-0: (αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide

Description: The chemical substance with the name "(αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide" and CAS number "1681056-61-0" is characterized by its complex molecular structure, which includes multiple functional groups such as sulfonamides, amides, and heterocycles. This compound features a quinoline moiety, which is known for its biological activity, particularly in medicinal chemistry. The presence of furan and thiophene rings suggests potential interactions with biological targets, making it of interest in drug development. The methoxy group may enhance lipophilicity, influencing the compound's pharmacokinetics. Additionally, the stereochemistry indicated by "(αR)" suggests that the compound has specific spatial arrangements that could affect its biological activity and interactions. Overall, this substance is likely to exhibit unique chemical properties and potential therapeutic applications, warranting further investigation in the context of pharmacology and medicinal chemistry.

Formula: C₂₈H₂₅N₃O₆S₂

InChI: InChI=1S/C28H25N3O6S2/c1-36-25-9-3-2-8-23(25)27(28(33)31(17-20-6-4-14-37-20)18-21-7-5-15-38-21)30-39(34,35)22-11-12-24-19(16-22)10-13-26(32)29-24/h2-16,27,30H,17-18H2,1H3,(H,29,32)/t27-/m1/s1

InChI key: InChIKey=IYIGLWQQAMROOF-HHHXNRCGSA-N

SMILES: O=C1C=CC=2C=C(C=CC2N1)S(=O)(=O)NC(C(=O)N(CC=3OC=CC3)CC=4SC=CC4)C=5C=CC=CC5OC

Synonyms:

• OSMI 1
• (αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide
• Benzeneacetamide, α-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-, (αR)-

OSMI-1

CAS: 1681056-61-0

• Formula: C₂₈H₂₅N₃O₆S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 563.6446

OSMI 1

CAS: 1681056-61-0

• Formula: C₂₈H₂₅N₃O₆S₂
• Color and Shape: Neat
• Molecular weight: 563.64

OSMI 1

CAS: 1681056-61-0

Inhibitor of O-GlcNAc transferase

• Formula: C₂₈H₂₅N₃O₆S₂
• Purity: Min. 95%
• Molecular weight: 563.65 g/mol

OSMI-1

CAS: 1681056-61-0

OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.

• Formula: C₂₈H₂₅N₃O₆S₂
• Purity: 96.79% - 99.83%
• Color and Shape: Solid
• Molecular weight: 563.64