CAS: 168266-90-8 - Vofopitant

Formula: C₂₁H₂₃F₃N₆O

InChI: InChI=1S/C21H23F3N6O/c1-31-18-10-9-16(30-20(21(22,23)24)27-28-29-30)12-15(18)13-26-17-8-5-11-25-19(17)14-6-3-2-4-7-14/h2-4,6-7,9-10,12,17,19,25-26H,5,8,11,13H2,1H3/t17-,19-/m0/s1

InChI key: InChIKey=XILNRORTJVDYRH-HKUYNNGSSA-N

SMILES: FC(F)(F)C1=NN=NN1C2=CC=C(OC)C(=C2)CNC3CCCNC3C=4C=CC=CC4

Synonyms:

• (2S,3S)-N-[[2-Methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-3-piperidinamine
• 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, (2S,3S)-
• 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, (2S-cis)-
• 3-piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-
• Gr 205171
• Vofopitant

GR 205171

CAS: 168266-90-8

Antagonist of neurokinin receptor NK1

• Formula: C₂₁H₂₃F₃N₆O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 432.44 g/mol

Vofopitant

CAS: 168266-90-8

Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for …

• Formula: C₂₁H₂₃F₃N₆O
• Purity: 97.61%
• Color and Shape: Solid
• Molecular weight: 432.44