CAS 168273-06-1: Rimonabant

Description: Rimonabant, with the CAS number 168273-06-1, is a selective cannabinoid receptor antagonist primarily known for its role in weight management and obesity treatment. It acts by blocking the CB1 receptors in the central nervous system, which are involved in appetite regulation and energy balance. This compound is characterized by its chemical formula C22H21Cl3N2O, and it features a complex structure that includes a tricyclic core. Rimonabant was initially marketed as an anti-obesity drug but was withdrawn from the market due to concerns about psychiatric side effects, including depression and anxiety. Its pharmacological profile also suggests potential applications in metabolic disorders, but the adverse effects have limited its use. Rimonabant is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Despite its withdrawal, research continues into its mechanisms and potential therapeutic uses, particularly in understanding the endocannabinoid system's role in various physiological processes.

Formula: C₂₂H₂₁Cl₃N₄O

InChI: InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)

InChI key: InChIKey=JZCPYUJPEARBJL-UHFFFAOYSA-N

SMILES: O=C(NN1CCCCC1)C2=NN(C3=CC=C(Cl)C=C3Cl)C(C=4C=CC(Cl)=CC4)=C2C

Synonyms:

• 1-(2,4-Dichlorophenyl)-5-(4-chlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
• 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-
• 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid N-(piperidin-1-yl)amide
• 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
• 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide
• 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
• 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide hydrochloride (1:1)
• A 281
• Acomplia
• Enp 9
• N-Piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide
• Rimonabant(Acomplia,Sr141716)
• Sr 141617
• Sr 141716
• Zimulti
• Rimonabant

Rimonabant

CAS: 168273-06-1

Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.

• Formula: C₂₂H₂₁Cl₃N₄O
• Purity: 98% - 99.91%
• Color and Shape: White Or Almost White Crystalline Powder
• Molecular weight: 463.79

5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide

CAS: 168273-06-1

• Formula: C₂₂H₂₁Cl₃N₄O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 463.7873

Rimonabant

CAS: 168273-06-1

• Formula: C₂₂H₂₁Cl₃N₄O
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 463.79

Rimonabant base

CAS: 168273-06-1

• Formula: C₂₂H₂₁Cl₃N₄O
• Purity: ≥ 97.5%
• Color and Shape: White to off-white powder or crystals
• Molecular weight: 463.79

Rimonabant

CAS: 168273-06-1

Cannabinoid receptor 1 (CB1) antagonist. Lowers consumption of food, via central and peripheral mechanisms. Reduces …

• Formula: C₂₂H₂₁Cl₃N₄O
• Color and Shape: Powder
• Molecular weight: 463.79 g/mol

Rimonabant - Bio-X ™

CAS: 168273-06-1

Rimonabant is cannabinoid receptor type 1 (CB1) inverse agonist drug. Rimonabant is used to treat …

• Formula: C₂₂H₂₁Cl₃N₄O
• Purity: Min. 99.0%
• Color and Shape: Powder
• Molecular weight: 463.79 g/mol