CAS 168286-98-4

7-hydroxycoumarin B-D-glucuronide,*sodium

Description:

7-Hydroxycoumarin B-D-glucuronide, sodium salt, is a chemical compound derived from the natural product coumarin, which is known for its various biological activities. This compound features a glucuronide moiety, which enhances its solubility and bioavailability, making it more suitable for biological applications. The presence of the sodium salt form indicates that it is likely used in aqueous solutions, facilitating its use in various biochemical assays or pharmacological studies. 7-Hydroxycoumarin itself is recognized for its fluorescent properties, which can be advantageous in analytical chemistry and biological imaging. The glucuronidation process typically serves to detoxify and facilitate the excretion of compounds in biological systems, suggesting that this derivative may play a role in metabolic pathways. Overall, 7-hydroxycoumarin B-D-glucuronide, sodium salt, is significant in research contexts, particularly in studies related to drug metabolism, pharmacokinetics, and the exploration of coumarin derivatives in therapeutic applications.

Formula: C₁₅H₁₃NaO₉

InChI: InChI=1/C15H14O9.Na/c16-9-4-2-6-1-3-7(5-8(6)23-9)22-15-12(19)10(17)11(18)13(24-15)14(20)21;/h1-5,10-13,15,17-19H,(H,20,21);/q;+1/p-1/t10?,11-,12?,13?,15+;/m1./s1

SMILES: c1cc(cc2c1ccc(=O)o2)OC1C(C(C(C(C(=O)O)O1)O)O)O.[Na]

β-D-Glucopyranosiduronic acid, 2-oxo-2H-1-benzopyran-7-yl, monosodium salt (9CI)

CAS: 168286-98-4

Formula: C₁₅H₁₃NaO₉

Purity: 97%

Color and Shape: Solid

Molecular weight: 360.2481

Ref: IN-DA001XYY

7-Hydroxy Coumarin Glucuronide Sodium Salt

CAS: 168286-98-4

Formula: C₁₅H₁₃O₉·Na

Color and Shape: White To Off-White Solid

Molecular weight: 337.26 22.99

Ref: 4Z-C-168

7-Hydroxycoumarin glucuronide sodium salt

CAS: 168286-98-4

7-Hydroxycoumarin glucuronide sodium salt

Molecular weight: 360.25g/mol

Ref: 54-BIA362

7-hydroxy Coumarin Glucuronide (sodium salt)

CAS: 168286-98-4

7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.

Formula: C₁₅H₁₄NaO₉

Color and Shape: Solid

Molecular weight: 361.258

Ref: TM-T37364

7-Hydroxy Coumarin-d5 Glucuronide Sodium Salt

CAS: 168286-98-4

Formula: C₁₅H₈D₅O₉·Na

Color and Shape: Off-White Solid

Molecular weight: 342.29 22.99

Ref: 4Z-C-163

7-Hydroxycoumarin glucuronide sodium salt

CAS: 168286-98-4

Formula: C₁₅H₁₃NaO₉

Purity: ≥ 97.0%

Color and Shape: White to light yellow solid

Molecular weight: 360.25

Ref: 7W-GC8704

Carbazochrome Impurity 9

CAS: 168286-98-4

Formula: C₉H₁₁NO₄S

Color and Shape: Off-White Solid

Molecular weight: 229.25

Ref: 4Z-C-163012

7-Hydroxy Coumarin-d5 beta-D-Glucuronide Sodium Salt

Controlled Product

CAS: 168286-98-4

Applications A labelled metabolite of 7-Ethoxycoumarin and Coumarin. Useful as a pharmacokinetic standard in metabolic studies.
References Blankson, E., et al.: Biochem. Pharmacol., 42, 1241 (1991), Steensma, A., et al.: Xenobiotica, 24, 893 (1994), Fisher, R., et al.: Toxicol. Methods, 5, 99 (1995), Ekins, S., et al.: Drug Metab. Dispos., 24, 990 (1996)

Formula: C₁₅H₈D₅NaO₉

Color and Shape: Neat

Molecular weight: 365.28

Ref: TR-H924882

7-Hydroxy Coumarin-13C6 beta-D-Glucuronide

Controlled Product

CAS: 168286-98-4

Applications A labelled metabolite of 7-Ethoxycoumarin and Coumarin. Useful as a pharmacokinetic standard in metabolic studies.
References Blankson, E., et al.: Biochem. Pharmacol., 42, 1241 (1991), Steensma, A., et al.: Xenobiotica, 24, 893 (1994), Fisher, R., et al.: Toxicol. Methods, 5, 99 (1995), Ekins, S., et al.: Drug Metab. Dispos., 24, 990 (1996)

Formula: C₉₁₃C₆H₁₃NaO₉

Color and Shape: Neat

Molecular weight: 366.2

Ref: TR-H924883

7-Hydroxy Coumarin beta-D-Glucuronide Sodium Salt

CAS: 168286-98-4

Stability Hygroscopic
Applications A metabolite of 7-Ethoxycoumarin and Coumarin. Useful as a pharmacokinetic standard in metabolic studies.
References Blankson, E., et al.: Biochem. Pharmacol., 42, 1241 (1991), Steensma, A., et al.: Xenobiotica, 24, 893 (1994), Fisher, R., et al.: Toxicol. Methods, 5, 99 (1995), Ekins, S., et al.: Drug Metab. Dispos., 24, 990 (1996)

Formula: C₁₅H₁₃O₉·Na

Color and Shape: White To Light Beige

Molecular weight: 360.25

Ref: TR-H924880

7-Hydroxycoumarin b-D-glucuronide sodium salt

CAS: 168286-98-4

7-Hydroxycoumarin b-D-glucuronide sodium salt is a metal ion chelator that has been shown to be synergistic with sulfate in the inhibition of virus replication. It does not inhibit the formation of ATP, but inhibits its utilization by competing for sulfate ions. 7-Hydroxycoumarin b-D-glucuronide sodium salt has also been shown to inhibit the formation of atp levels in protoplasts from rat thymus and liver. This substance is an analog of coumarin and is metabolized by glucuronidation and sulfation. The enzyme β-glucuronidase hydrolyzes 7-hydroxycoumarin b-D-glucuronide sodium salt, releasing 7-hydroxycoumarin, which can be excreted or further metabolized by oxidation or conjugation with glucuronic acid.

Formula: C₁₅H₁₃NaO₉

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 360.26 g/mol

Ref: 3D-MH09753

7-Hydroxy Coumarin Glucuronide Sodium Salt

CAS: 168286-98-4

Formula: C₁₅H₁₃O₉Na

Molecular weight: 337.26 : 23.0

Ref: ST-EA-CP-C246002