CAS 1684-40-8

9-amino-1,2,3,4-tetrahydroacridine hydro-chloride

Description:

9-Amino-1,2,3,4-tetrahydroacridine hydrochloride, with the CAS number 1684-40-8, is a chemical compound that belongs to the class of acridine derivatives. It is characterized by its bicyclic structure, which includes a fused ring system that contributes to its biological activity. This compound is typically encountered as a hydrochloride salt, enhancing its solubility in water and making it suitable for various applications in medicinal chemistry. 9-Amino-1,2,3,4-tetrahydroacridine is known for its potential neuroprotective properties and has been studied for its role in the treatment of neurodegenerative diseases, particularly Alzheimer's disease, due to its ability to inhibit acetylcholinesterase. The compound exhibits a range of pharmacological effects, including modulation of neurotransmitter systems. Its physical properties include a crystalline form, and it is generally handled with care due to its biological activity. As with many chemical substances, proper safety protocols should be followed when working with this compound in laboratory settings.

Formula: C₁₃H₁₅ClN₂

InChI: InChI=1/C13H14N2.ClH/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H

InChI key: InChIKey=ZUFVXZVXEJHHBN-UHFFFAOYSA-N

SMILES: NC1=C2C(=NC=3C1=CC=CC3)CCCC2.Cl

Synonyms:

• 1,2,3,4-Tetrahydro-9-aminoacridine hydrochloride
• 1,2,3,4-Tetrahydroacridin-9-Amine
• 1,2,3,4-Tetrahydroacridin-9-Aminium Chloride
• 5,6,7,8-Tetrahydroacridin-9-amine hydrochloride
• 9-Acridinamine, 1,2,3,4-tetrahydro-, hydrochloride (1:1)
• 9-Acridinamine, 1,2,3,4-tetrahydro-, monohydrochloride
• 9-Amino-1,2,3,4-Tetrahydroacridine hydrochloride
• Acridine, 9-amino-1,2,3,4-tetrahydro-, hydrochloride
• Acridine, 9-amino-1,2,3,4-tetrahydro-, monohydrochloride
• Ci 970
• Cognex
• Furfurylmercaptan
• Hydroaminacrine
• Romotal
• Tacrin hydrochloride
• Tacrine hydrochloride
• Tenakrin
• 1,2,3,4-TETRAHYDRO-5-AMINOACRIDINE HYDROCHLORIDE
• tetrahydroaminacrin
• tacrinhydrochloride
• ci970
• 1,2,3,4-tetrahydro-9-acridinaminmonohydrochloride
• 1,2,3,4-tetrahydro-9-amino-acridinmonohydrochloride
• TACRINE HCL
• 1,2,3,4-tetrahydro-9-aminoacridinehydrochloride
• 9-AMINO-1,2,3,4-TETRAHYDROACRIDINEHYDROC HLORIDE HY
• TACRINE
• 1,2,3,4-tetrahydroacridin-9-amine monohydrochloride
• 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE, MONOHYDROCHLORIDE
• 9-amino-1,2,3,4-tetrahydro-acridinhydrochloride

Tacrine hydrochloride

CAS: 1684-40-8

A potent centrally acting anticholinesterase for therapy of memory deficits in patients with Alzheimer's disease. THA also selectively blocks potassium channels in the central nervous system, which results in an increased release of acetylcholine and a prolongation of the action potential of the pre

Formula: C₁₃H₁₄N₂•HCl

Purity: 98+%

Color and Shape: Powder or crystals or crystalline powder

Molecular weight: 234.73(anhy)

Ref: 02-J60070

Tacrine Hydrochloride

CAS: 1684-40-8

Color and Shape: Neat

Ref: 61-FOR1982.00

9-Acridinamine, 1,2,3,4-tetrahydro-, hydrochloride (1:1)

CAS: 1684-40-8

Formula: C₁₃H₁₅ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 234.7246

Ref: IN-DA001Y1M

Tacrine hydrochloride

CAS: 1684-40-8

Tacrine: a cholinergic agonist, anticholinesterase; inhibits AChE/BChE with IC50s of 31/25.6 nM.

Formula: C₁₃H₁₅ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 234.73

Ref: TM-T22435

Tacrine (hydrochloride)

CAS: 1684-40-8

Tacrine (hydrochloride)

Purity: 98%

Molecular weight: 234.73g/mol

Ref: 54-OR1005484

Tacrine Hydrochloride

Controlled Product

CAS: 1684-40-8

Formula: C₁₃H₁₄N₂·ClH

Color and Shape: Neat

Molecular weight: 234.72

Ref: 86-MM1982.00

9-Amino-1,2,3,4-tetrahydroacridine Hydrochloride Dihydrate

Controlled Product

CAS: 1684-40-8

Applications A potent centrally acting anticholinesterase, for therapy of memory deficits in patients with Alzheimers's disease. THA also selectively blocks potassium channels in the central nervous system, which results in an increased release of acetylcholine and a prolongation of the action potential of the presynaptic cholinergic neurons.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Harper, J., et al.: Chem. Biol., 4, 119 ( 1997), Kirkitadze, M., et al.: J. Mol. Biol., 312, 1103 (2001), Zhuang, Z., et al.: J. Med. Chem., 44, 1905 (2001), Necula, M.J., et al.: Biol. Chem., 282, 10311 (2007),

Formula: C₁₃H₁₄N₂·ClH

Color and Shape: Neat

Molecular weight: 234.72

Ref: TR-A629700

1,2,3,4-Tetrahydroacridin-9-amine hydrochloride

CAS: 1684-40-8

Purity: 98.0%

Molecular weight: 234.72999572753906

Ref: 10-F496791