CAS 168611-18-5

5-Me-2'-OMe-U-CE Phosphoramidite

Description:

5-Me-2'-OMe-U-CE Phosphoramidite, with the CAS number 168611-18-5, is a specialized chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This phosphoramidite derivative features a 5-methyl group and a 2'-methoxy group on a uridine base, which enhances its stability and solubility in various solvents. The phosphoramidite functional group allows for efficient coupling reactions during oligonucleotide synthesis, facilitating the formation of phosphodiester bonds. Its unique structural modifications contribute to improved properties such as increased resistance to nucleases and enhanced binding affinity in hybridization assays. This compound is typically utilized in research and development settings, particularly in the synthesis of RNA and DNA sequences for applications in molecular biology, genetic engineering, and therapeutic development. As with many phosphoramidites, it is essential to handle this compound with care, following appropriate safety protocols due to its reactive nature.

Formula: C₄₁H₅₁N₄O₉P

Synonyms:

• 5-methyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methyl-Uridine-3'-CE-Phosphoramidite
• Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], (S)- (9CI)
• 5-Me-2'-OMe-U-CE Phosphoramidite

2'-OMe-5-Me-U ce-phosphoramidite

CAS: 168611-18-5

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Formula: C₄₁H₅₁N₄O₉P

Purity: Min. 95%

Molecular weight: 774.8 g/mol

Ref: 3D-TGA61118